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博文

目前显示的是标签为“CANCER”的博文

Genetically Targeted Fractionated Chemotherapy

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53967#.VN2pzyzQrzE Author(s)   Aaron J. Smith , John Oertle , Dino Prato *   Affiliation(s) Envita, Scottsdale, USA . ABSTRACT Complex and late stage cancer patients are in need of novel methods of selecting and administering chemotherapy particularly for those patients who are refractory to current treatment methods. The use of biomarkers to enhance decision making with regard to the molecular profile of a person’s cancer is becoming more important in the practice of oncology. The standard for the last several decades is to elect chemotherapeutic agents based on staging and histological identification of the primary cancer site alone versus utilizing the genetic and molecular profile information along with histological primary cancer site and staging to select chemotherapy regimens. Cancers are caused by mutations that occur within cells and th...

Two Grams BID Is an Oral Dosage of Vitamin C to Reduce the Risk of Recurrence of Superficial Bladder Carcinoma

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53879#.VNm_USzQrzE Author(s)  Edward Folk 1 , Tracy M. Downs 2 , Alfred Roc Ordman 3 Affiliation(s) 1 Beloit College Biochemistry Program, Beloit, USA . 2 Department of Urology, UW-Madison School of Medicine and Public Health, Madison, USA . 3 Beloit College, Beloit, USA . ABSTRACT Background: Continuous exposure to millimolar (mM) Vitamin C (AA) in vitro kills cancer cells. For superficial bladder carcinoma (SBC), standard chemotherapy is instillation of Bacillus Calmette-Guerin. The recurrence rate with this therapy is 91%. But high dosage vitamins including AA reduced the recurrence to 41%. Aim: To determine the oral dosage of AA that causes the highest concentration of AA [AA] in the bladder. Method: We conducted a clinical trial of 14 people who took various dosages of AA, and analyzed the [AA] in their urine. Results: AA above 2 g twice a day was not absorbed. B...

Cancer, Malnutrition and Cachexia: We Must Break the Triad

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53793#.VNMhYizQrz Author(s) Virender Suhag 1* , B. S. Sunita 2 , Arti Sarin 1 , A. K. Singh 1   Affiliation(s) 1 Army Hospital (Research & Referral), Delhi, India . 2 Base Hospital, Delhi, India . Many factors can modify nutritional status in cancer patients, including cachexia, nausea and vomiting, decreased caloric intake or oncologic treatments causing malabsorption. The cachexia-anorexia syndrome is a complex metabolic syndrome associated with cancer and some other palliative conditions characterized by involuntary weight loss involving fat and muscle, anorexia, early satiety, fatigue and weakness due to shifts in metabolism caus...