Differential Expression of Leptin and Leptin Receptor mRNA in Obese and Non-Obese Women across the Menstrual Cycle Title
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52899#.VKyRT8nQrzE Author(s) María-Raquel Huerta-Franco 1 , E. R. Huerta-Franco 2 , F. M. Vargas-Luna 3 Affiliation(s) 1 Department of Sciences Applied to the Work, University of Guanajuato, Leon, México . 2 Department of Dentistry, University of Guadalajara, Guadalajara, México . 3 Department of Physical Engineering, University of Guanajuato, Leon, México . ABSTRACT OBJECTIVE: The aim of this study was to investigate the messenger ribonucleic acid expression of leptin (L-mRNA) and the leptin receptor (OB-RmRNA) in subcutaneous fat tissue and to determine their relationship with leptin and testosterone and steroid serum levels over the course of the menstrual cycle (MC), in obese (OBW) and non-obese women (NOW). DESIGN: Observational study investigating mRNA transcript expression of leptin and the leptin receptor from human subcutaneous fat specimens...