Scientific Research Publishing

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=54043#.VOBO0yzQrzE Author(s)   Septian Hartono 1,2* , Choon Hua Thng 2 , Kai Hsiang Chuang 3 , Huynh Hung 4 , Tong San Koh 2   Affiliation(s) 1 School of Electrical & Electronic Engineering, Nanyang Technological University, Singapore City, Singapore . 2 Department of Oncologic Imaging, National Cancer Centre Singapore, Singapore City, Singapore . 3 Laboratory of Molecular Imaging, Singapore Bioimaging Consortium, Singapore City, Singapore . 4 Laboratory of Molecular Endocrinology, National Cancer Centre Singapore, Singapore City, Singapore . ABSTRACT Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has been widely applied to evaluate microcirculatory parameters in clinical settings. However, pre-clinical studies involving DCE-MRI of small animals remain challenging with the requirement for high spatial and temporal resolution for qu...

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=51241#.VGAaXWfHRK0 Author(s) Pooja S. Venkatadri , Charles C. Lee Affiliation(s) Department of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, USA . ABSTRACT Glutamatergic synaptic transmission is an essential component of neural circuits in the central nervous system. Glutamate exerts its effects by binding to various types of glutamate receptors, which are found distributed on neurons throughout the central nervous system. These receptors are broadly classified into two main groups, ionotropic glutamate receptors (iGluRs) and metabo-tropic glutamate receptors (mGluRs). U...

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=51047#.VFL8tWfHRK0 Author(s) Maria-Grazia Ascenzi 1 , Xia Du 1 , James I. Harding 1 , Emily N. Beylerian 2 , Brian M. de Silva 2 , Ben J. Gross 2 , Hannah K. Kastein 2 , Weiguang Wang 1 , Karen M. Lyons 1 , Hayden Schaeffer 3 Affiliation(s) 1 Department of Orthopaedic Surgery, University of California, Los Angeles, California, USA . 2 Department of Mathematics, University of California, Los Angeles, California, USA . 3 Department of Mathematics, University of California, Irvine, California, USA . ABSTRACT Microscopy imaging of mouse growth plates is extensively used in biology to understand the effect of specific molecules o...