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Gold Nanoparticle and Berberine Entrapped into Hydrogel Matrix as Drug Delivery System

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53192#.VLciWcnQrzE Author(s)    Camila Rufino Souza 1 , Henrique R. Oliveira 1 , Wagner M. Pinheiro 2 , Lubhandwa S. Biswaro 2 , Ricardo B. Azevedo 2 , Anderson J. Gomes 1* , Claure N. Lunardi 1*   Affiliation(s) 1 Laboratory of Nanobiotechnology, Faculty of Ceilandia, University of Brasilia, Brasilia, Brazil . 2 Institute of Biological Sciences, University of Brasilia, Brasilia, Brazil . ABSTRACT In this study the novel hydrogel loaded with gold nanoparticle (AuNP) enhanced the berberine (BS) release when compared with other formulations of hydrogel. Hydrogels are hydrophilic polymer networks having the capacity to absorb water, ranging from about twenty to thousand times their dry weight. BS is a natural product, a quaternary ammonium salt from the group of isoquinoline alkaloids found in medicinal plants as Berberis Vulgaris. BS has some activity...