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Immunotherapy of Cancer—A Historical Note

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=51253#.VGAezGfHRK0 Author(s)   Istvan Berczi 1,2 Affiliation(s) 1 Department of Immunology, University of Manitoba, Winnipeg, Canada . 2 Department of Physiology, The University of Aguascalientes, Aguascalientes, Mexico . ABSTRACT We examined the possibility that the anti-estrogens, tamoxifen (TX) and toremifen (TO) interacted   with the immune system. Indeed, both TX and TO stimulated cells mediated cytotoxicity reactions by various killer cells: killer T (TK), natural killer (NK), lymphokine activated killer (LAK) cells. Both TX and TO inhibited the growth of tumors that express estrogen receptors. Thus these antiestrogens in...