Clinical Implications of Tumor Necrosis Factor-Alpha, Interleukin-6 and Resistin in Coronary Artery Disease
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=48852#.VKIVucCAM4 Author(s) Qamar Javed Affiliation(s) Department of Biochemistry, Quaid-i-Azam University, Islamabad, Pakistan . ABSTRACT Tumor necrosis factor alpha (TNF-alpha) and interleukin-6 (IL-6) are involved in the progression of coronary artery disease (CAD). The cytokines’ levels are associated with the severity of CAD. We have recently reported on the association of resistin, a relatively novel cytokine with the pathogenesis of cardiovascular disease (CVD). Although the inflammatory cytokines’ impact on atherosclerosis is widely accepted, yet some controversy exists regarding the involvement of these factors i...