Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=54059#.VOBZiCzQrzE Author(s) Kent C. Sasse , David Warner * , Sean M. Ward , Walter Mandeville , Rebecca Evans Affiliation(s) Department of Physiology & Cell Biology, University of Nevada School of Medicine, Reno, USA . ABSTRACT Background: Staple line reinforcement material has been demonstrated to raise the burst pressure threshold after linear intestinal stapling. Numerous bioprosthetic materials have been utilized in surgical practice. Porcine urinary bladder matrix (ACell, Inc.) is an extracellular matrix material derived from porcine bladder used to reinforce surgically repaired soft tissue, and facilitate the body’s regenerative capacity. Objective: This study represents the first evaluation of urinary bladder matrix in gastrointestinal staple line reinforcement. Methods: Pathogen-free pigs underwent midline laparotomy under general anesthesia. Small inte...
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