Computational Analysis of Physicochemical, Pharmacokinetic and Toxicological Properties of Deoxyhypusine Synthase Inhibitors with Antimalarial Activity
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52193#.VIj-bcnQrzE Author(s) Nayara S. R. Silva 1 , Luana K. S. Gonçalves 1 , Jonatas L. Duarte 1 , Juliane S. Silva 1 , César F. Santos 1 , Francinaldo S. Braga 1 , Raí C. Silva 1 , Josivan S. Costa 1 , Lorane I. S. Hage-Melim 1,2 , Cleydson B. R. dos Santos 1,2* Affiliation(s) 1 Laboratory of Modeling and Computational Chemistry, Federal University of Amapá, Campus Universitário Marco Zero, Macapá, Brazil . 2 Postgraduate Program in Pharmaceutical Sciences, Federal University of Amapá, Macapá, Brazil . ABSTRACT Malaria is a parasitic disease which has as etiological agents protozoa of the genus Plasmodium prevalent in tropi...