Scientific Research Publishing

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53396#.VMCLTCzQrzE Author(s)    Satyanarayana Battu , Vasudev Pottabathini Affiliation(s) Department of Chemistry, University College of Science, Osmania University, Hyderabad, India . ABSTRACT Lansoprazole degradation is accelerated in both acidic and basic medium in water. The present investigation deals with the hydrolytic degradation of Lansoprazole. Acidic medium degradation show all known impurities and degradation products whereas basic degradation studies show new impurity which has higher molecular weight than Lansoprazole. New impurity was identified, isolated using mass based auto purification system and characterised by 1 H NMR, 13 C NMR, HMBC, HSQC, NOE, COSY and HRMS experiments. Isolated impurity was showing molecular weight of 467.10, molecular formula of C 23 H 16 F 3 N 5 OS and its name is 7-(3-Methyl-4-(2,2,2-trifluoroethoxy) pyrid...

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52915#.VKyaksnQrzE Author(s)    Zephania Simon , Kelvin Mtei , Amare Gessesse , Patrick A. Ndakidemi *   Affiliation(s) School of Life Sciences and Bioengineering, The Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania . ABSTRACT Soil bacteria1 called rhizobia are gram-negative capable to colonize the soil immediately surrounding roots under the influence of the plant “rhizosphere” and reduce atmospheric nitrogen into the form available to plants through nitrogen fixation process. Nitrogen is the most limiting and supplied nutrient to most plants, and the determinant of plant growth. Legumes differ with most plants because they have access to nitrogen from both mineral and symbiotic sources. Small-scale farmers who are the major legume producers in Africa rarely apply fertilizers during legume production. Hence, the cro...