Scientific Research Publishing

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53967#.VN2pzyzQrzE Author(s)   Aaron J. Smith , John Oertle , Dino Prato *   Affiliation(s) Envita, Scottsdale, USA . ABSTRACT Complex and late stage cancer patients are in need of novel methods of selecting and administering chemotherapy particularly for those patients who are refractory to current treatment methods. The use of biomarkers to enhance decision making with regard to the molecular profile of a person’s cancer is becoming more important in the practice of oncology. The standard for the last several decades is to elect chemotherapeutic agents based on staging and histological identification of the primary cancer site alone versus utilizing the genetic and molecular profile information along with histological primary cancer site and staging to select chemotherapy regimens. Cancers are caused by mutations that occur within cells and th...

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53582#.VMnd2CzQrzE Author(s)    Stephanie Fryar-Williams 1,2,3,4 , Jörg E. Strobel 1   Affiliation(s) 1 The University of Adelaide, Adelaide, Australia . 2 The Queen Elizabeth Hospital, Woodville, Australia . 3 Basil Hetzel Institute for Translational Health Research, Woodville, Australia . 4 Youth in Mind Research Institute, Norwood, Australia . ABSTRACT Background: Neuroscience can assist clinical understanding and therapy by finding neurobiological markers for mental illness symptoms. Objectives: To quantify biomarkers for schizophrenia and schizoaffective disorder and relate these to discrete symptoms of psychosis. Methods: Within a case-control design with multiple exclusion criteria to exclude organic causes and confounding variables, 67 DSM IV-R diagnosed and 67 control participants from a defined hospital, clinic and community catchment are...