Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50811#.VE29MlfHRK0 Author(s) Márcio Shigeaki Mito , Cristiane Vizioli de Castro , Rosane Marina Peralta , Adelar Bracht Affiliation(s) Laboratory of Liver Metabolism, Department of Biochemistry, University of Maringá, Maringá, Brazil . ABSTRACT The action mechanism of ranolazine, an antiangina drug, could be at least partly metabolic, including inhibition of fatty acid oxidation and stimulation of glucose utilization in the heart. The purpose of the present work was to investigate if ranolazine affects hepatic carbohydrate metabolism. For this purpose, the hemoglobin-free isolated perfused rat liver was used as the experim...
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