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博文

目前显示的是标签为“Genotyping”的博文

Human Nail Clippings as a Source of DNA for Genetic Studies

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53415#.VMG65izQrzE Author(s)    Le Truong 1 , Hannah Lui Park 1* , Seong Sil Chang 1 , Argyrios Ziogas 1 , Susan L. Neuhausen 2 , Sophia S. Wang 2 , Leslie Bernstein 2 , Hoda Anton-Culver 1   Affiliation(s) 1 Department of Epidemiology, Genetic Epidemiology Research Institute, University of California, Irvine, CA, USA . 2 Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA . ABSTRACT Blood samples have traditionally been used as the main source of DNA for genetic analysis. How-ever, this source can be difficult in terms of collection, transportation, and long-term storage. In this study, we investigated whether human nail clippings could be used as a source of DNA for SNP genotyping, null-allele detection, and whole-genome amplification. From extracted nail DNA, we achieved amplico...

Application of High-Throughput Sequencing: Discovery of Informative SNPs to Subtype Bacillus anthracis

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=47443#.VFnEDWfHRK0 Author(s) Guillaume Girault , Simon Thierry , Emeline Cherchame , Sylviane Derzelle Affiliation(s) University Paris-Est, ANSES, Animal Health Laboratory, Bacterial Zoonoses Unit, Maisons-Alfort, France . University Paris-Est, ANSES, Animal Health Laboratory, Bacterial Zoonoses Unit, Maisons-Alfort, France . University Paris-Est, ANSES, Animal Health Laboratory, Bacterial Zoonoses Unit, Maisons-Alfort, France . University Paris-Est, ANSES, Animal Health Laboratory, Bacterial Zoonoses Unit, Maisons-Alfort, France . ABSTRACT Single Nucleotide Polymorphisms (SNPs) are the most common and abundant genetic variation f...