HDL-Mediated Protection of Coronary Vasodilator Response to Adenosine in the Hypercholesterolemic Swine
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=51835#.VHfUEWfHRK0 Author(s) Federico Vozzi 1 , Gualtiero Pelosi 1* , Mariarita Puntoni 1 , Federica Viglione 1 , Silvia Rocchiccioli 1 , Claudia Kusmic 1 , Fabio Bernini 2 , Paolo Marraccini 1 , Maria Giovanna Trivella 1 , Oberdan Parodi 1 Affiliation(s) 1 Institute of Clinical Physiology IFC-CNR, Pisa, Italy . 2 Sant’Anna School of Advanced Studies, Pisa, Italy . ABSTRACT It is known that high-cholesterol diet impairs coronary vasodilatation in animal models of athe-rosclerosis irrespective of overt pathology. We evaluated the specific role of LDL and HDL on adenosine-elicited coronary vasodilatation after short time (10...