Altered Neurogranin Phosphorylation and Protein Levels are Associated with Anxiety- and Depression-Like Behaviors in Rats Following Forced Swim Stress
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=51699#.VHVkUmfHRK0 ' Author(s) Huanhuan Li 1,2 , Wenjuan Lin 1* , Junfa Li 3 , Weiwen Wang 1 Affiliation(s) 1 Brain-Behavior Research Center, Institute of Psychology, Chinese Academy of Sciences, Beijing, China . 2 Department of Psychology, Renmin University of China, Beijing, China . 3 Department of Neurobiology, Capital University of Medical Sciences, Beijing, China . ABSTRACT Here we tested the hypothesis that stress-induced alterations in Neurogranin (Ng) synthesis and/ or utilization might underlie stress-related depression and anxiety. Rats were randomly divided into five conditions: chronic swim stress (CS), acute swim...