Reducing Participation Bias in Case-Control Studies: Type 1 Diabetes in Children and Stroke in Adults
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=48508#.VD9_ZFfHRK0 Author(s) Claire Keeble , Stuart Barber , Paul David Baxter , Roger Charles Parslow , Graham Richard Law Affiliation(s) Division of Epidemiology & Biostatistics, University of Leeds, Leeds, UK . Department of Statistics, University of Leeds, Leeds, UK . ABSTRACT Background: Case-control studies have been used extensively in determining the aetiology of rare diseases. However, case-control studies often suffer from participation bias in the control group, resulting in biased odds ratios that cause problems with interpretation. Participation bias can be hard to detect and is often ignored. Methods: Population data can be used in pla...