Evaluation of Reproductive Characteristics of 21 Highly Inbred Lines of White Leghorns Divergently Selected for or Segregating in Tumor Resistance
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53169#.VLcvk8nQrzE Author(s) Gururaj Kulkarni , Huanmin Zhang * Affiliation(s) USDA, Agriculture Research Service, Avian Disease and Oncology Laboratory, East Lansing, USA . ABSTRACT Reproduction performance of 21 inbred experimental lines of White Leghorns was evaluated based on samples of reproduction records over a period of eight consecutive years. Two lines (63 and 72) have been extensively used in studies, especially in research seeking for genetic and epigenetic factors underlying resistance to avian tumor virus-induced diseases in chickens. The other 19 lines are recombinant congenic strains (RCS), which were generated by crossing lines 63 and 72 followed by two consecutive backcrosses to the line 63 and then full-sib mating. In theory, each RCS processes 7/8 of progenitor background line 63 genome and a random sample (1/8) of the progenit...