Rapid and Sensitive CZE Method for Quality Control Analysis of Pharmaceuticals Containing Pseudoephedrine, Triprolidine and Paracetamol
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=47156#.VGBOvmfHRK0 Author(s) Sonia Di Berardino , Renata Jasionowska Affiliation(s) Department of Chemistry, Sapienza University, Rome, Italy . Department of Chemistry, Sapienza University, Rome, Italy . ABSTRACT A rapid and sensitive CZE (Capillary Zone Electrophoresis) method for pharmaceutical analysis was developed and fully validated. The active compounds: Pseudoephedrine hydrochloride (PSE), Triprolidine hydrochloride (TRI) and Paracetamol (PAR) were separated and quantitatively determined using the tris-borate 30 mM buffer at pH = 9.0 as a Background Electrolyte (BGE). The electrophoretic separation was carried out at 25 ...