Scientific Research Publishing

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53192#.VLciWcnQrzE Author(s)    Camila Rufino Souza 1 , Henrique R. Oliveira 1 , Wagner M. Pinheiro 2 , Lubhandwa S. Biswaro 2 , Ricardo B. Azevedo 2 , Anderson J. Gomes 1* , Claure N. Lunardi 1*   Affiliation(s) 1 Laboratory of Nanobiotechnology, Faculty of Ceilandia, University of Brasilia, Brasilia, Brazil . 2 Institute of Biological Sciences, University of Brasilia, Brasilia, Brazil . ABSTRACT In this study the novel hydrogel loaded with gold nanoparticle (AuNP) enhanced the berberine (BS) release when compared with other formulations of hydrogel. Hydrogels are hydrophilic polymer networks having the capacity to absorb water, ranging from about twenty to thousand times their dry weight. BS is a natural product, a quaternary ammonium salt from the group of isoquinoline alkaloids found in medicinal plants as Berberis Vulgaris. BS has some activity...

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53026#.VLR_iMnQrzE Author(s)    Chikara Yoshida , Tomoki Ito , Ryosuke Anzai , Kengo Fukuda , Keita Kinoshita , Seiichi Sonotaki , Taku Takami , Yoshihiko Murakami Affiliation(s) Department of Organic and Polymer Materials Chemistry, Faculty of Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan . ABSTRACT We have developed a hybrid hydrogel that is formed from a crosslinkable polymeric micelle and a polyamine. Under optimal conditions, the hydrogel rapidly formed in one second after a crosslinkable polymeric micelle solution was mixed with a polyamine solution. We could change the hydrogel’s gelation properties, such as the storage modulus and gelation time by tuning the molecular weights of block copolymers and by tuning the pH of the dissolving-solvent of the hydrogel’s constituent components. Furthermore, we have clarified he...