Scientific Research Publishing

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53300#.VLydhcnQrzE Author(s)    Ashraf M. Mahmoud 1,2* , Noha N. Atia 1 , Salwa R. El-Shabouri 1 , Wesam M. El-Koussi 1   Affiliation(s) 1 Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt . 2 Department of Pharmaceutical Chemistry, College of Pharmacy, Najran University, Najran, KSA . ABSTRACT Simple and sensitive stability-indicating high performance thin layer chromatography (HPTLC) assay was developed and validated for quantitative determination of the antibacterial drug, gemifloxacin mesylate (GFX) in presence of its degradation products and ambroxol hydrochloride. The chromatographic separation was performed on HPTLC precoated silica gel plate 60F 254 as stationary phase. The mobile phase consisted of a mixture of ethyl acetate: methanol: 25% ammonia, (8:4.5:3, v/v/v). The detection was ...

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52968#.VK3xYMnQrzE Author(s)   Jude O. Ighere , Karina Honjoya , Ramesh C. Chawla Affiliation(s) Chemical Engineering Department, Howard University, Washington DC, USA . ABSTRACT This paper discusses the toxicity and mobility of chromium species. And it presents the extent and kinetics of reductive remediation of hexavalent chromium, Cr + using ferrous ion, Fe 2+ . Molar ratios of 1:3 and 1:6 of Cr (VI) to Fe (II) were used. Integral method of data analysis showed reaction followed second-order kinetics with R square values near unity. Reaction was initially fast but with a rapid precipitation attributed to Cr (III)-Fe (III) in previous studies. This colloidal precipitate ultimately stops the reaction, which explains while conversion efficiency increases with increased molar ratio of Cr (VI) to Fe (II). The impact of pH was investigated by adjusting the C...

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52387#.VJOMGcCAM4 Author(s)   Mohammed Nazeerunnisa 1 , Lakshmi Garikapati 2 , Syama Sundar Bethanabhatla 1,3* Affiliation(s) 1 Department of Chemistry, Acharya Nagarjuna University, Guntur, India . 2 Centre for Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Hyderabad, India . 3 Yogi Vemana University, Kadapa, India . ABSTRACT An isocratic stability-indicating reversed phase high performance liquid chromatographic method (RP-HPLC) was developed for determination of process related impurities and assay of darifenacin hydrobromide (DRF) in bulk drugs. DRF was subjected to various stress conditions such as hydrol...

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=47215#.VFw2uGfHRK0 Author(s) Bouamar Baghdad , A. Taleb , A. Carlo Iñigo Iñigo , H. El Hadi , M. Dalimi Affiliation(s) Department Natural Resources and Environment, Agronomic and Veterinary Institute-Hassan II, Rabat, Morocco . Department Natural Resources and Environment, Agronomic and Veterinary Institute-Hassan II, Rabat, Morocco . Instituto de Recursos Naturales y Agrobiología de Salamanca (IRNASA), Consejo Superior de Investigaciones Científicas (CSIC), Salamanca, Spain . Laboratory of Applied Geology, Geomatics and Environment, Faculty of Science of Ben M’Sik, Hassan II University, Casablanca, Morocco . Department of Chemistry, Faculty of Science and Technology, University Hassan II, Mohammedia, M...

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50970#.VFG4IFfHRK0 Author(s) Shashikant B. Landge , Sanjay A. Jadhav , Shrihari P. Vishwambar , Pavankumar V. Solanki , Saroj R. Bembalkar , Vijayavitthal T. Mathad * Affiliation(s) Research and Development, Megafine Pharma (P) Ltd., Nashik, India . ABSTRACT A rapid, specific, sensitive, and precise reverse-phase UPLC method developed for the quantitative determination of an atypical antipsychotic drug Iloperidone and its eight potential impurities in drug substances and drug products is described in this report. Chromatographic separation was achieved on a Waters Acquity UPLC® HSS C18 (2.1 mm × 100 mm, 1.8 micron) column the...

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50611#.VEcnmVfHRK0 Author(s)    Pramod Gopinathan Nair 1* , Swathy Vijayakumar 2 , Teena Lisluke 2 , Menacheri Sunil Paul Mathew 3 , Charuvila Thankappan Aravindakumar 3 Affiliation(s) 1 Department of Chemistry, NSS Hindu College, Changanassery, India . 2 Department of Chemistry, Christian College, Chenganoor, India . 3 School of Environmental Sciences, Mahatma Gandhi University, Kottayam, India . ABSTRACT Due to an increasing environmental pollution, a search for the cost effective treatment and disposal of the dyes from the textile effluents is getting more and more importance. Oxidation and reduction processes play impor...