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博文

目前显示的是标签为“Antipsychotics”的博文

Antipsychotic Medication and Risk of QTc Prolongation: Focus on Multiple Medication and Role of Cytochrome P450 Isoforms

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50717#.VEmpg1fHRK0 Author(s)     Takashi Ikeno 1,2* , Kiyotaka Kugiyama 2 , Hiroto Ito 1,2 Affiliation(s) 1 Department of Social Psychiatry, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan . 2 Faculty of Medicine, Graduate School of Medical Science, University of Yamanashi, Yamanashi, Japan . ABSTRACT Objective: To identify the effects of antipsychotics on QTc prolongation in light of age, gender, antipsychotic combination pattern, antipsychotic doses and cytochrome P450 (CYP) mediation, using large database describing the antipsychotic treatment of patients with schizophre...

Broader Role for Antipsychotics in the Treatment of Obsessive Compulsive Disorder and Schizophrenia—A Malaysian Case Series

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50307#.VDXf_FfHRK0 Author(s)   Benedict Francis 1 , Stephen Thevananthan Jambunathan 1,2 , Subash Kumar Pillai 1 Affiliation(s) 1 Department of Psychiatry, University Malaya Medical Center, Kuala Lumpur, Malaysia . 2 The Mind Faculty, Solaris Mont Kiara, Kuala Lumpur, Malaysia . ABSTRACT Obsessive compulsive disorder (OCD) and schizophrenia have been considered to be variants of the same disorder. At the advent of psychiatry, there was a distinction between neurotic, mood disorders and psychotic disorders. As perceptions and thoughts evolve in this dynamic field, there has been a paradigm shift in the way these disorders are being perceived. Of particular interest...