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博文

目前显示的是标签为“Adipogenesis”的博文

Effect of Androstenedione on Adipogenesis in Murine C3H10T1/2 Mesenchymal Cells

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53872#.VNm4LyzQrzE Author(s)  Pandurangan Ramaraj 1* , Jorge N. Artaza 2 , Indrani Sinha-Hikim 2 , Wayne E. Taylor 2,3   Affiliation(s) 1 Department of Biochemistry, Kirksville College of Osteopathic Medicine, A.T. Still University of Health Sciences, Kirksville, MO, USA . 2 Division of Endocrinology, Charles R. Drew University of Medicine and Science, Los Angeles, CA, USA . 3 Department of Health and Life Sciences, Charles R. Drew University of Medicine and Science, Los Angeles, CA, USA . ABSTRACT Clinical trials of weak androgen androstenedione (AD) administered at a high concentration, showed an increase in muscle mass in men like strong androgens testosterone (T) and dihydrotestosterone (DHT), but did not show any inhibitory effect on fat mass unlike strong androgens. This observation prompted us to check the in-vitro effect of AD on adipogenesis u...