Effects of Vitamin K-1 and Menaquinone-7 on Vascular Function and Blood Pressure in Warfarin-Induced Calcification-Model in Rats
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=51202#.VFspzGfHRK0 Author(s) Aino Siltari 1 , Niko Wickholm 1 , Anne S. Kivimäki 1 , Kaisa Olli 2 , Krista Salli 2 , Kirsti Tiihonen 2 , Riitta Korpela 1 , Heikki Vapaatalo 1 Affiliation(s) 1 Institute of Biomedicine, Pharmacology, University of Helsinki, Helsinki, Finland . 2 DuPont Nutrition and Health, Kantvik Active Nutrition, Kantvik, Finland . ABSTRACT Given that vascular calcification is inversely correlated with the clinical intake of menaquinone, a rat model of warfarin-induced calcification may be useful for testing menaquinone and vitamin K-1 potential effects on vascular function. The aim of the present study was...