Biogenic Amine Neurotransmitter Response to Morphine in the Anterior Cingulate Cortex Predicts Propensity for Acquiring Self-Administration and the Intensity of the Withdrawal Syndrome
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50585#.VEX3AlfHRK0 Author(s) Maria Trigub 1 , Vladinir Kudrin 2 , Valentina Bashkatova 1 , Petr Klodt 2 , Sergey Sudakov 1 Affiliation(s) 1 P. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia . 2 V. V. Zakusov Research Institute of Pharmacology, Moscow, Russia . ABSTRACT Individual differences in behavioral characteristics or initial responses to abused drugs had been recently demonstrated to have predictive value in the propensity of later abuse. The research described here was initiated to determine the initial response of rats to administration of morphine if the physiological response has predi...