Deterministic Parsing Model of the Compound Biological Effectiveness (CBE) Factor for Intracellular 10Boron Distribution in Boron Neutron Capture Therapy
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52141#.VIplS8nQrzE Author(s) Shintaro Ishiyama Affiliation(s) Quantum Beam Science Directorate, Japan Atomic Energy Agency, Naka-gun, Japan . ABSTRACT Purpose: In defining the biological effects of the 10 B( n , α ) 7 Li neutron capture reaction, we have previously developed a deterministic parsing model to determine the Compound Biological Effectiveness ( CBE ) factor in Borono-Phenyl-Alanine ( BPA )-mediated Boron Neutron Capture Therapy ( BNCT ). In present paper, we demonstrate that the CBE factor is directly and unambiguously derivable by the new formula for any case of intracellular 10 Boron ( 10 B) distribution, which...