Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=48650#.VK4Vm8nQrzE Author(s) Stephen McGrath , Piers Yates , Gareth Prosser Affiliation(s) Department of Orthopaedic Surgery, Fremantle Hospital, Fremantle, Australia . Department of Orthopaedic Surgery, Fremantle Hospital, Fremantle, Australia . Department of Orthopaedic Surgery, Fremantle Hospital, Fremantle, Australia . ABSTRACT Intravenous Tranexamic acid has been shown to decrease blood transfusion requirements in sur- gery. Little evidence exists regarding the much cheaper oral form. The objective of this cohort study was to evaluate whether oral tranexamic acid administration in patients undergoing elec- tive hip and knee replacement surgery resulted in decreased transfusion requirements. Methods: We assessed the transfusion requirements of 332 patients following unilateral total hip or knee arthroplasty, with the first 140 receiving no tranexamic acid an...
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