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博文

目前显示的是标签为“Sodium Phenylbutyrate”的博文

Preliminary Findings on the Use of Targeted Therapy with Pazopanib and Other Agents in Combination with Sodium Phenylbutyrate in the Treatment of Glioblastoma Multiforme

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52600#.VJyu-cCAM4 Author(s)      Stanislaw R. Burzynski * , Tomasz J. Janicki , Gregory S. Burzynski , Sheldon Brookman Affiliation(s) Burzynski Clinic, Houston, USA . ABSTRACT The most common and aggressive type of brain tumor is glioblastoma multiforme (GBM). The prognosis for GBM remains poor with a five-year survival rate between 1% and 2%. The prospects for patients with recurrent GBM (RGBM) are much worse, with the majority dying within 6 months. This publication provides a brief description of the treatment of 11 GBM patients treated with sodium phenylbutyrate (PB) in combination with pazopanib, m-TOR inhibi...

Preliminary Findings on the Use of Targeted Therapy in Combination with Sodium Phenylbutyrate in Advanced Malignant Mesothelioma: A Strategy for Improved Survival

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50986#.VFHN_FfHRK0 Author(s) Stanislaw R. Burzynski , Tomasz J. Janicki , Gregory S. Burzynski , Sheldon Brookman Affiliation(s) Burzynski Clinic, Houston, TX, USA . ABSTRACT Advanced malignant mesothelioma (MM) is among the most aggressive and difficult-to-treat diseases. Industrialization and exposure to asbestos is the main causative factor for the dramatic increase in the incidence of MM, which carries a poor prognosis and a median survival of less than 12 months. Combination chemotherapy offers only palliative results; however, targeted therapy carries more promise for future successful treatment. This paper presents preliminar...

Preliminary Findings on the Use of Targeted Therapy in Combination with Sodium Phenylbutyrate in Recurrent Advanced Pancreatic Cancer—A Potential Strategy for Improved Survival

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50936#.VFCBKlfHRK0 Author(s)    Stanislaw R. Burzynski , Tomasz J. Janicki , Gregory S. Burzynski , Sheldon Brookman Affiliation(s) Burzynski Clinic, Houston, TX, USA . ABSTRACT Metastatic pancreatic cancer carries an estimated five-year survival rate of only 2%. Gemcitabine-based chemotherapy remains a first-line standard-of-care treatment for elderly patients with advanced pancreatic cancer. Combination chemotherapy FOLFIRINOX offers better results, but it is not recommended for the older patient population due to substantial toxicity. Standard-of-care second-line treatment is not yet established and is used in approximate...