The Possible Mechanisms Involved in the Protection Strategies against Radiation-Induced Cellular Damage by Carnitines
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53873#.VNm4MSzQrzE Author(s) Ashraf Virmani 1 , Andreas Diedenhofen 2 Affiliation(s) 1 Research, Innovation and Development, Sigma-Tau Health Science International BV, Utrecht, The Netherland . 2 International Division, Sigma-Tau SpA, Rome, Italy . ABSTRACT There is constant low level background radiation from the cosmos but in certain situation the body may be subjected to increased acute or chronic exposure from other sources. This occurs in situations such as radiation accidents, medical use and could possibly occur in military/terrorist incident. Dependent on the type, strength of the actual source, degree of exposure and type of radiation different strategies may be employed to reduce damage to the body tissues. A number of pharmacological agents such as peroxisome proliferator-activated receptor (PPAR) gamma agonists, diltiazem, amifos...