Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=54116#.VO2HpizQrzE Author(s) Tarek M. Abdel-Rahman * Affiliation(s) Cardiology Department, El Minia University Hospital, Minya, Egypt . ABSTRACT Objective : Clopidogrel therapy is the standard of care in patients with unstable angina. However, a percentage of subjects are nonresponders to clopidogrel and this leads to increased adverse outcome. On the other way round, some responsive patients are exposed to bleeding complications. Detection of both in daily practice is important in order to tailor the treatment protocol. In this study we aimed to estimate the cutoff value of mean platelet volume (MPV) for both platelet responsiveness and bleeding risks. Methods : The study was planned as a prospective cohort study. A total number of 230 patients admitted to our CCU with unstable angina over a period of one year (from June 2013 to May 2014) w...
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