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博文

目前显示的是标签为“Alkylphenol”的博文

Comparative Interactions of Anesthetic Alkylphenols with Lipid Membranes

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52726#.VKIClcCAM4 Author(s)   Hironori Tsuchiya 1* , Maki Mizogami 2 Affiliation(s) 1 Department of Dental Basic Education, School of Dentistry, Asahi University, Mizuho, Japan . 2 Department of Anesthesiology and Reanimatology, Faculty of Medical Sciences, University of Fukui, Eiheiji-cho, Japan . ABSTRACT Objective: While substituted phenols have a variety of pharmacological activity, the mechanism underlying their anesthetic effects remains uncertain especially about the critical target. We characterized the lipid membrane-interacting properties of different phenols by comparing with general anesthetic propofol and local an...