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目前显示的是标签为“Hepatocytes”的博文

Cell-Specific Effects of Ethanol on Nitric Oxide Synthase Induced by Inflammatory Mediators

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52879#.VKtMh8nQrzE Author(s)     Patience O. Obih 1* , Barry J. Potter 2 Affiliation(s) 1 College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA . 2 Department of Physiology, Louisiana State University Health Sciences Center, New Orleans, LA, USA . ABSTRACT To examine the pro- and anti-oxidant properties of nitric oxide (NO) production in alcoholic liver disease, we compared the effects of ethanol pretreatment (24 hrs, 100 mM concentration in a dedicated CO 2 incubator) on the induction of inducible NO synthase and its activity in a cell culture system. We employed two types of liver cells as mode...