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博文

目前显示的是标签为“Angiogenesis”的博文

Messages from the Border: Novel Insights in Signal Transduction Pathways Involved in Tumor Invasion and Metastasis

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53972#.VN2sTSzQrzE Author(s)   Michele Ciccarelli 1 , Mariarosaria Rusciano 2 , Daniela Sorriento 3 , Angela Serena Maione 2 , Maria Soprano 2 , Guido Iaccarino 1,4 , Maddalena Illario 2*   Affiliation(s) 1 Department of Medicine and Surgery, University of Salerno, Salerno, Italy . 2 Department of Clinical and Translational Medicine, Federico II University, Napoli, Italy . 3 IBP, CNR, Napoli, Italy . 4 IOS e Coleman, Napoli, Italy . ABSTRACT Cancer is a multistep process encompassing the transformation of normal epithelial cells to the stromal invasion and metastasis, with these last considered the final stage of the disease. Tumor invasiveness is based on creation of a specific peri-tumoral environment which on turn depends upon epithelial-stromal interactions, degradation of extracellular matrix and reorganization of fibrillar components. Even thou...

Analysis on a Mathematical Model for Tumor Induced Angiogenesis

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=47221#.VFw0bWfHRK0 Author(s) Richard C. Ewool , Zachariah Sinkala Affiliation(s) Department of Computational Science & Mathematics, Middle Tennessee State University, Murfreesboro, USA . Department of Computational Science & Mathematics, Middle Tennessee State University, Murfreesboro, USA . ABSTRACT Tumor-induced angiogenesis is the process by which unmetastasized tumors recruit red blood vessels by way of chemical stimuli to grow towards the tumor for vascularization and metastasis. We model the process of tumor-induced angiogenesis at the tissue level using ordinary and partial differential equations (ODEs and PDEs) that ...

The Use of Transcatheter Laser Exposure in the Treatment of Cerebral Vessels Hypoplasia Accompanied by Migraine

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50408#.VD4bG1fHRK0 Author(s)   Ivan V. Maksimovich Affiliation(s) Clinic of Cardiovascular Diseases Named after Most Holy John Tobolsky, Moscow, Russia . ABSTRACT The research is dedicated to the possibility of restoring cerebral blood supply in patients with brain vessels hypoplasia accompanied by migraine. The research involved 67 patients aged 29 - 58 (average age 42) with severe migraine. The examination plan included laboratory diagnostics, assessment of dementia severity (CDR), assessment of cognitive impairment (MMSE), cerebral computed tomography (CT), cerebral magnetic resonance imaging (MRI), cerebral scintigraphy (SG), rheoencephalography (REG), ce...