Flow Cytometer Performance Characterization, Standardization and Calibration against CD4 on T Lymphocytes Enables Quantification of Biomarker Expressions for Immunological Applications
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=48151#.VEXyOVfHRK0 Author(s) Heba Degheidy , Steven Bauer , Gerald Marti , Lili Wang Affiliation(s) Center for Biologics Evaluation and Research, US Food and Drug Administration (FDA), Bethesda, Maryland, USA . Center for Biologics Evaluation and Research, US Food and Drug Administration (FDA), Bethesda, Maryland, USA . Center for Devices and Radiological Health, FDA, Silver Spring, Maryland, USA . National Institute of Standards and Technology (NIST), Gaithersburg, Maryland, USA . ABSTRACT There is an urgent need for developing a procedure for biomarker standardization and relative quantificationin clinical laboratories. Measurin...