Dynamic Contrast-Enhanced MRI of Mouse Liver: A Feasibility Study Using a Dual-Input Two-Compartment Tracer Kinetic Model
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=54043#.VOBO0yzQrzE Author(s) Septian Hartono 1,2* , Choon Hua Thng 2 , Kai Hsiang Chuang 3 , Huynh Hung 4 , Tong San Koh 2 Affiliation(s) 1 School of Electrical & Electronic Engineering, Nanyang Technological University, Singapore City, Singapore . 2 Department of Oncologic Imaging, National Cancer Centre Singapore, Singapore City, Singapore . 3 Laboratory of Molecular Imaging, Singapore Bioimaging Consortium, Singapore City, Singapore . 4 Laboratory of Molecular Endocrinology, National Cancer Centre Singapore, Singapore City, Singapore . ABSTRACT Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has been widely applied to evaluate microcirculatory parameters in clinical settings. However, pre-clinical studies involving DCE-MRI of small animals remain challenging with the requirement for high spatial and temporal resolution for qu...