跳至主要内容

博文

目前显示的是标签为“Breast Cancer”的博文

Genotoxic and Cytotoxic Damage by Cyclophosphamide and Adriamycin as a Response to Treatment in Breast Cancer Patients: Pilot Study

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53822#.VNR6JSzQrzE Author(s)   Jimena Garibay-Garcia 1 , Fernando Mejia-Sanchez 1 , Eduardo Ramírez-San-Juan 2 , Miriam V. Flores-Merino 1 , Julieta Castillo-Cadena 1   Affiliation(s) 1 Research Center in Medical Science, Autonomous University of the State of Mexico, Toluca, Mexico . 2 National School in Biological Science, Instituto Politécnico Nacional, Mexico City, Mexico . ABSTRACT The aim of this study was to evaluate the genotoxicity induced by cyclophosphamide-adriamycin treatment in breast cancer patients through the frequencies of Sister Chromatid Exchange (SCE), Replication Index (RI), Mitotic Index (MI) and Cell Proliferation Index (CPI) and to study the possible association between biomarkers of genotoxicity and the early response to treatment. The frequencies were obtained before and immediately after therapy from 17 patients with breas...

Risk Factors for Breast Cancer of Different Age Groups: Moroccan Data?

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53690#.VM83QCzQrzE Author(s)     Fatima Zahra Laamiri 1 , Abdellatif Bouayad 2 , Nadia Hasswane 3 , Samir Ahid 4 , Mustapha Mrabet 1 , Barkat Amina 1   Affiliation(s) 1 Faculty of Medicine and Pharmacy/Research Team in Maternal and Child Health and Nutrition, Mohammed V University, Rabat, Morocco . 2 Laboratory of Immunology, Institut Pasteur of Morocco, Casablanca, Morocco . 3 Faculty of Medicine and Pharmacy/Hospital Sidilahsen, Temara, Morocco . 4 The Faculty of Medicine and Pharmacy and the Pharmacy Unit at the National Institute of Oncology, Rabat, Morocco . ABSTRACT Background: Several epidemiological studies have been carried to identify the risk factors for developing breast cancer. The aim of this study was to evaluate the risk factors associated with breast cancer in different age groups in the Moroccan women and to determine susceptible...

An Autoantibody Based Protein Microarray Blood Test to Enhance the Specificity of a Negative Screening Mammogram

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53458#.VMW12yzQrzE Author(s)     T. M. Allweis 1 , L. Strauss 2 , Z. Malyutin 2 , A. Bassein Kapov-Kagan 2 , I. Novikov 2 , T. B. Bevers 3 , S. Iacobelli 4 , M. T. Sandri 5 , A. Bitterman 6 , P. Engelman 7 , B. Piura 2 , M. Rosenberg 8 , G. Yahalom 1* Affiliation(s) 1 Kaplan Medical Center, Rehovot, Israel . 2 Eventus Diagnostics (Israel) LTD, Ora, Israel . 3 University of Texas, MD Anderson Cancer Center, Houston, USA . 4 Media Pharma Srl, Chieti, Italy . 5 Laboratory Medicine Division, Istituto Europeo di Oncologia, Milan, Italy . 6 Carmel Medical Center, Surgery A, Haifa, Israel . 7 Zvulun Breast Center, Clalit Organization, Kiryat Bialik, Israel . 8 Eventus Diagnostics Inc., Miami, USA . ABSTRACT Background: Current screening mammography for breast cancer is associated with misdiagnosis in as many as 30% of cases. Objectives: To develop and c...

The Association of Night Shift Work with the Development of Breast Cancer in Women

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53385#.VMBtkyzQrzE Author(s)   P. I. J. Moukangoe , M. S. Jansen van Rensburg Affiliation(s) Independent Consultants, Johannesburg, South Africa . ABSTRACT Breast cancer is a serious public health concern in South Africa and globally. It is estimated that one in seven South Africans will develop cancer in their lifetime. According to a case-controlled study, 80% of cancer cases are thought to be due to external, non-inherited factors, which could potentially have been prevented. The objectives of the current case-control study were: 1) to determine the relationship between night shift work and the development of breast cancer; 2) to explore the relationship between night shift work and other types of cancer; 3) to explore any difference between night shift work and breast cancer, and night shift work and other types of cancer. A total of 106 research part...

Observer Variability in BI-RADS Ultrasound Features and Its Influence on Computer-Aided Diagnosis of Breast Masses

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53047#.VLSJdsnQrzE Author(s)   Laith R. Sultan 1* , Ghizlane Bouzghar 1 , Benjamin J. Levenback 1 , Nauroze A. Faizi 1 , Santosh S. Venkatesh 2 , Emily F. Conant 1 , Chandra M. Sehgal 1   Affiliation(s) 1 Department of Radiology, University of Pennsylvania, Philadelphia, USA . 2 Department of Electrical Engineering, University of Pennsylvania, Philadelphia, USA . ABSTRACT Objective: Computer classification of sonographic BI-RADS features can aid differentiation of the malignant and benign masses. However, the variability in the diagnosis due to the differences in the observed features between the observations is not known. The goal of this study is to measure the variation in sonographic features between multiple observations and determine the effect of features variation on computer-aided diagnosis of the breast masses. Materials and Methods: Ultrasoun...