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Two Grams BID Is an Oral Dosage of Vitamin C to Reduce the Risk of Recurrence of Superficial Bladder Carcinoma

Read  full  paper  at:
http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53879#.VNm_USzQrzE

Author(s) 
Edward Folk1, Tracy M. Downs2, Alfred Roc Ordman3

Affiliation(s)
1Beloit College Biochemistry Program, Beloit, USA.
2Department of Urology, UW-Madison School of Medicine and Public Health, Madison, USA.
3Beloit College, Beloit, USA.

ABSTRACT
Background: Continuous exposure to millimolar (mM) Vitamin C (AA) in vitro kills cancer cells. For superficial bladder carcinoma (SBC), standard chemotherapy is instillation of Bacillus Calmette-Guerin. The recurrence rate with this therapy is 91%. But high dosage vitamins including AA reduced the recurrence to 41%. Aim: To determine the oral dosage of AA that causes the highest concentration of AA [AA] in the bladder. Method: We conducted a clinical trial of 14 people who took various dosages of AA, and analyzed the [AA] in their urine. Results: AA above 2 g twice a day was not absorbed. But that intake produced a bladder [AA] above 1 mM in all participants. Conclusion: Taking 2 g of AA BID will increase [AA] in the bladder to a level likely to kill cancer cells that cause SBC. Taking that dosage 2 consecutive days a week is likely to reduce the recurrence rate of SBC substantially.

KEYWORDS
Cancer, Vitamin C, LUTS, Superficial Bladder Carcinoma

Cite this paper
Folk, E. , Downs, T. and Ordman, A. (2015) Two Grams BID Is an Oral Dosage of Vitamin C to Reduce the Risk of Recurrence of Superficial Bladder Carcinoma. Journal of Cancer Therapy, 6, 169-176. doi: 10.4236/jct.2015.62019.

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