跳至主要内容

Nutrient Analysis Critical Control Point (NACCP): Hazelnut as a Prototype of Nutrigenomic Study

The globalization of trade has increased the chances that the food produced in one place can affect the health and diet of people living in another. And the rapid increase of knowledge on nutrition, medicine and plant biotechnology has dramatically changed the concepts about food.

The NACCP process involves a sequence of analysis and controls that depart from raw material production to the evaluation of the effect of nutrition on health. It is articulated through the following points: 1) identification of nutrient level in the food; 2) identification of critical control points (environmental, genetic data, chemical and physical data, production technology, distribution and administration); 3) establishing critical limits that can impoverish and damage the nutrient; 4) establishing measures to monitor; 5) establishing corrective actions.

The aim of this study was to apply the Nutrient Analysis Critical Control Point (NACCP) process to ensure that the highest nutrient levels in food can determine a beneficial effect on the health of the consumer. The authors selected as biomarkers the total phenolic content (TPC) and total antioxidant capacity (TAC) of genotyped Italian hazelnut cultivars (Corylus e avellana L.). They performed a clinical study evaluating: a) nutritional status; b) clinical-biochemical parameters; c) low density lipoprotein oxidation (LDL-ox); d) the expression level changes of oxidative stress pathway genes in the blood cell at baseline and after 40 g/die of hazelnut consumption.

In the study, the authors found a significant lowering (p ≤ 0.005) of LDL oxidized proteins, in association with the consumption of 40 g/d of hazelnuts. Also, they found a significant variation (p ≤ 0.005) of gene expression of antioxidant and pro-oxidant genes, between the intake of dietary with and without hazelnuts.

In short, the nutritional quality of hazelnuts, identified by TPC and TAC, is in a certain way transferred to the consumer, as demonstrated by the results of gene expression and LDL oxidation, giving to diet the health qualities. And the results support the hypothesis that the NACCP process could be applied to obtain significant benefits in terms of primary prevention and for contributing to the amelioration of food management at the consumer level.

Article by Laura Di Renzo, et al, from Italy.

Full access: http://mrw.so/faRdc
Image by Ina Tsitovich, from Flickr-cc.

评论

此博客中的热门博文

Electron Spin and Proton Spin in the Hydrogen and Hydrogen-Like Atomic Systems

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52202#.VIj7tMnQrzE Author(s) Stanisław Olszewski * Affiliation(s) Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland . ABSTRACT The mechanical angular momentum and magnetic moment of the electron and proton spin have been calculated semiclassically with the aid of the uncertainty principle for energy and time. The spin effects of both kinds of the elementary particles can be expressed in terms of similar formulae. The quantization of the spin motion has been done on the basis of the old quantum theory. It gives a quantum number n = 1/2 as the index of the spin state acceptable for both the electron and proton ...

Remarks on the Complexity of Signed k-Domination on Graphs

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53574#.VMnXsCzQrzE Author(s)    Chuan-Min Lee 1 , Cheng-Chien Lo 1 , Rui-Xin Ye 2 , Xun Xu 2 , Xiao-Han Shi 2 , Jia-Ying Li 2 Affiliation(s) 1 Department of Computer and Communication Engineering, Ming Chuan University, The First American University in Asia, Taoyuan, Taiwan, Chinese Taipei . 2 Department of Electronic Information Engineering, Fuzhou University, Fuzhou, China . ABSTRACT This paper is motivated by the concept of the signed k-domination problem and dedicated to the complexity of the problem on graphs. For any fixed nonnegative integer k, we show that the signed k-domination problem is NP-complete for doubly chordal graphs. For strongly chordal graphs and distance-hereditary graphs, we show that the signed k-domination problem can be solved in polynomial time. We also show that the problem is linear-time solvable for trees, interval graphs, and chord...

A Review of Technical Requirements for High Penetration of Wind Power Systems

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52361#.VJN8VcCAM4 Author(s)    Yuan-Kang Wu 1 , Tung-Ching Lee 2 , Ting-Yen Hsieh 2 , Wei-Min Lin 2 Affiliation(s) 1 Department of Electrical Engineering, National Chung-Cheng University, Chiayi, Taiwan . 2 Green Energy and Environment Research Laboratories, Industrial Technology Research Institute, Hsinchu, Taiwan . ABSTRACT Renewable portfolio targets have been established in many regions around the world. Regional targets such as 20% renewable energy by year 2020 are not uncommon. As the levels of wind power penetration increase, there are many power system impacts. This work investigated possible challenges and technic...