Anorexia
Nervosa (AN) is a psychological and possibly life-threatening eating disorder
defined by an extremely low body weight relative to stature, extreme and
needless weight loss, illogical fear of weight gain, and distorted perception
of self-image and body. Among eating disorders, anorexia nervosa has been
proving a difficult condition, with many patients remaining ill for many years.
The purpose of this study was to elucidate clinical factors
influencing quality of life (QOL) in anorexia nervosa (AN) patients.
Twenty female
patients with AN (median age = 30.0 years old, quartile deviation = 6.8) and
forty female healthy controls (HC) (median age = 30.0 years old, quartile
deviation = 8.6) participated in the study. QOL was assessed with the 36-Item
Short Form Health Survey (SF-36) and social support was evaluated using the
Multidimensional Scale of Perceived Social Support (MSPSS). Clinical symptoms
were evaluated with the Structured Interview Guide for the Hamilton Depression
Rating Scale (SIGH-D) and the Eating Disorder Inventory-2 (EDI-2).
Scores of the SF-36 Mental
Component Summary (MCS) (U = 124.0, P < 0.0001)
and Role/Social Component Summary (RCS) (U = 223.0, P =
0.006) and scores of total (U = 108.0, P <
0.0001) and subscales of the MSPSS were lower in AN group than HC group, and
the SIGH-D score was higher (U = 46.0, P <
0.0001) in AN group than HC group. Scores of the SIGH-D (ρ = −0.565, P <
0.05) and subscales of the EDI-2 Interoceptive Confusion (ρ = −0.556, P <
0.05), Interpersonal Difficulty (ρ = −0.581, P <
0.05) and Negative Self-image (ρ = −0.617, P <
0.05) were negatively correlated to MCS, and score of Interoceptive Confusion
subscale showed a negative correlation to RCS (ρ = −0.672, P <
0.05). Moreover, stepwise regression analysis showed that the SIGH-D score was
an independent predictor of MCS and Interoceptive Confusion score predicted
RCS.
In conclusion, the
results suggest that not only depressive symptoms but also poor emotional
awareness and impaired sense of control are much more important as influencing
factors on AN patients’ QOL than other clinical factors.
Article by Chikako
Kane, et al, from Japan.
Full access: http://mrw.so/dYCBa
Image by Joakim, from Flickr-cc.
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