Heart Failure with Preserved Ejection Fraction: A Report about 64 Cases Followed at the Heart Institute of Abidjan
The concept of heart failure with
preserved ejection fraction is relatively new.
Historically, the diagnosis of heart failure was based primarily on clinical
criteria, and patients described in the studies were likely to be a mixture of
heart failure with altered ejection fraction and heart failure with preserved
ejection fraction. For little work has been done on this type of heart
failure in Africa, it is appropriate to describe the epidemiological and
etiological features of this condition.
This was a
retrospective study that was carried out over a 12-month period,
from 1 January 2015 to 31 December 2015, in the hospitalization department of
the Heart Institute of Abidjan. It was about patients hospitalized for heart
failure who had received a dose of NT-proBNP and who had had an
electrocardiogram and a Doppler echocardiography. Heart failure with preserved
ejection fraction (HFPEF) was defined from the symptoms and signs of heart
failure, the level of NT-proBNP and from echocardiography data based on the
left ventricular ejection fraction (LVEF) > 50%, the dilatation of the left
atrium. The diastolic dysfunction of the left ventricle was assessed by the
ratio E/E’ > 13. We defined as heart failure with decreased ejection
fraction (HFDEF) symptoms and signs of heart failure and left ventricular
dysfunction LVEF < 40%. A computer file was completed. It
included epidemiological and etiological data.
The study involved sixty-four
patients with heart failure with preserved ejection fraction out of 257
patients with heart failure that is a prevalence of 25%. The mean age was 57.3 ±
16 years old. There was a male predominance that was 52% of cases. Congestive
heart failure was predominant in 67%. NT-proBNP levels were 365 pg/ml on
average. The average length of stay was 5.5 ± 3.1. Intra-hospital deaths were 4.6%.
The etiologies are dominated by high blood pressure in 85.9%, followed by
obesity in 28.1%, then by ischemic heart disease in 4.6%. There were no
diabetic patients in this group.
In conclusion, heart failure with
preserved ejection fraction is characterized in the regions by its frequent occurrence
in the congestive mode in young hypertensive men. And complications of high
blood pressure occur early and severe in the African black subject.
Article by Fatoumata
Traore, et al, from Heart
Institute of Abidjan, Abidjan, Côte d’Ivoire.
Full access: http://mrw.so/3eT72p
Image by Shannon Brien, from
Flickr-cc.
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