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A Case Report of Pediatric Epstein Barr Virus (EBV) Related Cholestasis from Al-Adan Hospital, Kuwait

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ABSTRACT
Infectious mononucleosis is an acute illness due to Epstein Barr virus infection, which occurs commonly in young adults. Liver involvement in acute EBV infection occurs in up to 95% of patients between the 6th and 15th day of illness and is usually mild [1]. Here we report on a 7 years old girl treated by Gastroenterology, Hepatology, and Nutrition Unit of Al-Adan Hospital pediatric Department, presented with prolonged fever, lymphadenopathy, generalized edema, hyperbilurubi- nemia and elevated liver enzymes secondary to EBV infection. This case represents a rare presentation of common viral infection in pediatric population.
Cite this paper
Al-Refaee, F. , Al-Enezi, S. , Hoque, E. and Albadrawi, A. (2015) A Case Report of Pediatric Epstein Barr Virus (EBV) Related Cholestasis from Al-Adan Hospital, Kuwait. Open Journal of Pediatrics, 5, 23-26. doi: 10.4236/ojped.2015.51005.
 
References
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[2]Barlow, G., Kilding, R. and Green, S. (2000) Epstein-Barr Virus Mimicking Extra-Hepatic Biliary Obstruction. Journal of the Royal Society of Medicine, 93, 316-318.
 
[3]Jenson, H.B. (2000) Acute Complications of Epstein-Barr Virus Infectious Mononucleosis. Current Opinion in Pediatrics, 12, 263-268. http://dx.doi.org/10.1097/00008480-200006000-00016
 
[4]Hoagland, R.J. (1955) The Transmission of Infectious Mononucleosis. The American Journal of the Medical Sciences, 3, 229-262.
 
[5]Anagnostopoulos, I., Hummel, M., Kreschel, C. and Stein, H. (1995) Morphology, Immunophenotype, and Distribution of Latently and/or Productively Epstein-Barr Virus-Infected Cells in Acute Infectious Mononucleosis: Implications for the Interindividual Infection Route of Epstein-Barr Virus. Blood, 85, 744-750.
 
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[7](1972) General Features of Infectious Mononucleosis (Roundtable Discussion). In: Glade, P.R., Ed., Infectious Mononucleosis: Proceedings of Symposium, New York, 7 April 1972, Philadelphia, JB Lippincott, 1-18.
 
[8]Shaukat, A., Tsai, H.T., Rutherford, R. and Anania, F.A. (2005) Epstein-Barr Virus Induced Hepatitis: An Important Cause of Cholestasis. Hepatology Research, 33, 24-26.
http://dx.doi.org/10.1016/j.hepres.2005.06.005
 
[9]Juttner, H.U., Ralls, P.W., Quinn, M.F., et al. (1982) Thickening of the Gall-Bladder Wall in Acute Hepatitis: Ultrasound Demonstration. Radiology, 142, 465-466. http://dx.doi.org/10.1148/radiology.142.2.7054838
 
[10]Patel, S., Zuckerman, M. and Smith, M. (2003) Real-Time Quantitative PCR of Epstein-Barr Virus BZLF1 DNA Using the LightCycler. Journal of Virological Methods, 109, 227-233.
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[11]Yamada, K. and Yamada, H. (2001) Gallbladder Wall Thickening in Mononucleosis Syndromes. Journal of Clinical Ultrasound, 29, 322-325. http://dx.doi.org/10.1002/jcu.1042                  eww150210lx
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