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Transarterial Embolization Using Pingyangmycin-Lipiodol Emulsion (PLE) for Treatment of Focal Nodular Hyperplasia of the Liver and 1-Year Follow-Up: A Case Report and Literature Review

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http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53032#.VLSC0cnQrzE

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ABSTRACT
Focal nodular hyperplasia (FNH) is a common benign hepatic tumor which is often treated non-operatively until it appears apparent symptoms such as pain and upper abdominal distension. We report here a case of trans-catheter arterial embolization (TAE) using pingyangmycin-lipiodol emulsion (PLE) for blocking a fatal bleeding originated from percutaneous biopsy as well as for FNH treatment. After embolization by means of the mixture of PLE and particles of gelfoam, the bleeding was stopped and the FNH was apparently shrinked 1 year later. TAE using PLE may be considered as a safe and effective method for the treatment of FNH.
 
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Qiu, J. , Wen, S. , Luo, L. , Chen, P. and Guo, W. (2015) Transarterial Embolization Using Pingyangmycin-Lipiodol Emulsion (PLE) for Treatment of Focal Nodular Hyperplasia of the Liver and 1-Year Follow-Up: A Case Report and Literature Review. Case Reports in Clinical Medicine, 4, 1-5. doi: 10.4236/crcm.2015.41001.
 
References
[1]Navarro, A.P., Gomez, D., Lamb, C.M., Brooks, A. and Cameron, I.C. (2014) Focal Nodular Hyperplasia: A Review of Current Indications for and Outcomes of Hepatic Resection. HPB (Oxford), 16, 503-511.
http://dx.doi.org/10.1111/hpb.12169
 
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http://dx.doi.org/10.2214/AJR.13.11856
 
[3]Huang, D., Chen, Y., Zeng, Q., Zhao, J., Wu, R., et al. (2011) Transarterial Embolization Using Pingyangmycin Lipiodol Emulsion and Polyvinyl Alcohol for the Treatment of Focal Nodular Hyperplasia of the Liver. Hepatogastroenterology, 58, 1736-1741.
http://dx.doi.org/10.5754/hge11174
 
[4]Donadon, M., Di Tommaso, L., Roncalli, M. and Torzilli, G. (2013) Multiple Focal Nodular Hyperplasias Induced by Oxaliplatin-Based Chemotherapy. World Journal of Hepatology, 5, 340-344.
 
[5]Pupulim, L.F., Vullierme, M.P., Paradis, V., Valla, D., Terraz, S., et al. (2013) Congenital Portosystemic Shunts Associated with Liver Tumours. Clinical Radiology, 68, e362-e369.
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[8]Chen, W.L., Huang, Z.Q., Zhang, D.M. and Chai, Q. (2010) Percutaneous Sclerotherapy of Massive Venous Malformations of the Face and Neck Using Fibrin Glue Combined with OK-432 and Pingyangmycin. Head Neck, 32, 467-472.
 
[9]Gu, L., Huang, D.Y., Fu, C.J., Wang, Z.L., Liu, Y., et al. (2013) Intralesional Injection of Pingyangmycin plus Corticosteroids May Be an Effective Treatment for Cheilitis Granulomatosa. Medical Hypotheses, 81, 729-730.
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[10]Zeng, Q., Li, Y., Chen, Y., Ouyang, Y., He, X., et al. (2004) Gigantic Cavernous Hemangioma of the Liver Treated by Intra-Arterial Embolization with Pingyangmycin-Lipiodol Emulsion: A Multi-Center Study. CardioVascular and Interventional Radiology, 27, 481-485.
http://dx.doi.org/10.1007/s00270-003-2754-2                                                                 eww150113lx

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