Determination of Exposure to Medical and Industrial Toxic Chemicals from Beijing by Human Hair, Nail and Blood Analysis
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http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52923#.VKygQsnQrzE
Affiliation(s)
1School of Medicine, Tongji University, Shanghai, China.
2Departement of Chemistry, University of Pierre et Marie-Curie, Paris, France.
3AFPreMed, Toxicology Research Group, Toulouse, France.
2Departement of Chemistry, University of Pierre et Marie-Curie, Paris, France.
3AFPreMed, Toxicology Research Group, Toulouse, France.
ABSTRACT
The
aim of the present work was to investigate the exposure to the medical
and industrial toxic chemicals. The research was carried out on hair,
nail and blood samples in a panel of 40 healthy volunteers aged 7 to 77
with an average of 45 ± 19 years (18 women (45%) and 22 men (55%)). All
of these individuals had not received medication for at least 1 year,
including antibiotics and psychotropic. This study was realized from
July 2013 to March 2014 in Beijing, China. The method for an accurate
and reliable screening of medical and an industrial toxic chemical was
based on detection and assay by ultra-high performance liquid
chromatography with UV detection type of diode arrays. Also more than
10,000 toxic molecules commonly found in western industrial countries
were screened by coupling gas chromatography and mass spectrometry. The
main results indicate that the molecules analyzed are mainly antibiotic
(Gentamycine and Tobramycine), antidepressant (Amitriptylin and its
metabolites), narcotic (MDMA and Clonitazene), ingredient in cosmetics
(Benzenediol and Benzoic acid), insecticide (Carbamate derivative),
ketamine, chlorhexidine and phthalate derivatives. There are no detailed
documented baseline data of the analysis of medical and Industrial
toxic pollutants in hair, nail and blood samples in Beijing; however,
this study should be completed on samples from other provinces of China.
This study is the first of its kind. Therefore, further studies should
be conducted in other cities and provinces of China to be compared with
each other.
KEYWORDS
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References
Yang,
G. , Kechkeche, D. , Belhadj-Tahar, H. and Sadeg, N. (2015)
Determination of Exposure to Medical and Industrial Toxic Chemicals from
Beijing by Human Hair, Nail and Blood Analysis. Forensic Medicine and Anatomy Research, 3, 27-31. doi: 10.4236/fmar.2015.31006.
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