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Application of Total Error Strategy in Validation of Affordable and Accessible UV-Visible Spectrophotometric Methods for Quality Control of Poor Medicines

Read  full  paper  at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53326#.VL3BYyzQrzE Author(s)    Jérémie Kindenge Mbinze 1,2 , Jean Nsangu Mpasi 2 , Elza Maghe 2 , Sébastien Kobo 2 , Rodrigue Mwanda 2 , Guy Mulumba 2 , Jacquie Bolavie Bolande 3 , Trésor Menanzambi Bayebila 2 , Maguy Borive Amani 4 , Philippe Hubert 1 , Roland Djang’eing’a Marini 1,4   Affiliation(s) 1 University of Liege (ULg), Department of Pharmacy, CIRM, Laboratory of Analytical Chemistry, Liège, Belgium . 2 Laboratory of Drug Analysis, Faculty of Pharmaceutical Sciences, University of Kinshasa, Kinshasa, Democratic Republic of Congo . 3 Laboratory Service, Institute of Research in Science of Health, Kinshasa, Democratic Republic of Congo . 4 Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of Congo . ABSTRACT In the framework of fighting against the poor quality medicines sold in developing countries using ...

Development and Validation of a Stability-Indicating RP-HPLC Method for Determination of Darifenacin Hydrobromide in Bulk Drugs

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52387#.VJOMGcCAM4 Author(s)   Mohammed Nazeerunnisa 1 , Lakshmi Garikapati 2 , Syama Sundar Bethanabhatla 1,3* Affiliation(s) 1 Department of Chemistry, Acharya Nagarjuna University, Guntur, India . 2 Centre for Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Hyderabad, India . 3 Yogi Vemana University, Kadapa, India . ABSTRACT An isocratic stability-indicating reversed phase high performance liquid chromatographic method (RP-HPLC) was developed for determination of process related impurities and assay of darifenacin hydrobromide (DRF) in bulk drugs. DRF was subjected to various stress conditions such as hydrol...

Rapid and Sensitive CZE Method for Quality Control Analysis of Pharmaceuticals Containing Pseudoephedrine, Triprolidine and Paracetamol

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=47156#.VGBOvmfHRK0 Author(s) Sonia Di Berardino , Renata Jasionowska Affiliation(s) Department of Chemistry, Sapienza University, Rome, Italy . Department of Chemistry, Sapienza University, Rome, Italy . ABSTRACT A rapid and sensitive CZE (Capillary Zone Electrophoresis) method for pharmaceutical analysis was developed and fully validated. The active compounds: Pseudoephedrine hydrochloride (PSE), Triprolidine hydrochloride (TRI) and Paracetamol (PAR) were separated and quantitatively determined using the tris-borate 30 mM buffer at pH = 9.0 as a Background Electrolyte (BGE). The electrophoretic separation was carried out at 25 ...

Validation of the Greek Version of Perceived Stress Questionnaire: Psychometric Properties and Factor Structure in a Population-Based Survey

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=48880#.VDcrv1fHRK0 Author(s)    Eva Karatza , Dimitra Kourou , Michael Galanakis , Liza Varvogli , Christina Darviri Affiliation(s) Postgraduate Course Stress Management and Health Promotion, School of Medicine, University of Athens, Athens, Greece . Postgraduate Course Stress Management and Health Promotion, School of Medicine, University of Athens, Athens, Greece . Department of Psychology, Panteion University of Social and Political Sciences, Athens, Greece . Postgraduate Course Stress Management and Health Promotion, School of Medicine, University of Athens, Athens, Greece . Postgraduate Course Stress Management and Health Promotion, School of Medicine, University of Athens, Athens, Greece . ...