跳至主要内容

Post-Procedure Mortality after Cardiovascular Treatment Procedures in Patients with Pneumoconiosis

Read  full  paper  at:
http://www.scirp.org/journal/PaperInformation.aspx?PaperID=54063#.VOBZySzQrzE

Author(s)  
 
ABSTRACT
Pneumoconiosis (PNC) is a major occupational disease that develops as a result of occupational exposure to dust via inhalation. In addition to its harmful effects on the respiratory system, PNC can increase vulnerability to coronary heart disease (CHD)—the leading cause of death in the United States and in the world. Currently, two types of cardiovascular intervention procedures for CHD treatment are percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG). The objective of this study was to investigate comparative effectiveness of the two major cardiovascular intervention procedures—PCI and CABG—in PNC patients with CHD. Data from 1094 hospitalizations of adult patients with PNC and CHD (CHD-PNC patients) and 534,120 hospi-talizations of CHD patients without PNC (CHD-nonPNC) were investigated. Adjusted odds ratios for in-hospital death in relation to the type of procedure, adjusted for patient socio-demographic and clinical characteristics and hospital characteristics, were calculated using multivariable logistic regression. Men constituted 97.8% of CHD-PNC patients and 68.6% of CHD-nonPNC patients. Within the CHD-PNC group, crude (unadjusted) in-hospital mortality after CABG and PCI did not differ significantly (1.35% vs. 2.00%, p = 0.425) and remained insignificant in the multivariable analysis, adjusted for patient and hospital characteristics (adjusted OR = 0.714, 95% CI 0.220 - 2.323, p = 0.576). But in the CHD-nonPNC group, in-hospital mortality after CABG was significantly higher than after PCI both in crude analysis (2.83% vs. 1.28%, p < 0.001) and adjusted analysis (adjusted OR = 1.637, 95% CI 1.541 - 1.738, p < 0.001). The study results indicate that CABG is as safe as PCI in male CHD-PNC patients, in terms of in-hospital mortality. Further studies investigating comparative effectiveness of cardiovascular procedures in PNC patients using more detailed data are warranted.
 
Cite this paper
Sergeev, A. (2015) Post-Procedure Mortality after Cardiovascular Treatment Procedures in Patients with Pneumoconiosis. Occupational Diseases and Environmental Medicine, 3, 10-16. doi: 10.4236/odem.2015.31002.
 
References
[1]National Institute for Occupational Safety and Health (2014) Occupational Respiratory Disease Surveillance: National Occupational Respiratory Mortality System (NORMS). Centers for Disease Control and Prevention (CDC). http://webappa.cdc.gov/ords/norms.html
 
[2]Weinberger, S. (1998) Principles of Pulmonary Medicine. 3rd Edition, W.B. Saunders Company, Philadelphia.
 
[3]Bordow, R., Ries, A. and Morris, T., Eds. (2001) Manual of Clinical Problems in Pulmonary Medicine. 5th Edition, Lippincott Williams & Wilkins, Philadelphia.
 
[4]National Research Council and Institute of Medicine (2008) Respiratory Disease Research at NIOSH: Reviews of Research Programs of the Institute for Occupational Safety and Health. The National Academies Press, Washington DC.
 
[5]Go, A.S., Mozaffarian, D., Roger, V.L., Benjamin, E.J., Berry, J.D. and Borden, W.B. (2013) Heart Disease and Stroke Statistics—2013 Update: A Report from the American Heart Association. Circulation, 127, e6-e245. http://dx.doi.org/10.1161/CIR.0b013e318282ab8f
 
[6]World Health Organization (2008) The Global Burden of Disease: 2004 Update. WHO Press, Geneva.
 
[7]Landen, D.D., Wassell, J.T., McWilliams, L. and Patel, A. (2011) Coal Dust Exposure and Mortality from Ischemic Heart Disease among a Cohort of U.S. Coal Miners. American Journal of Industrial Medicine, 54, 727-733. http://dx.doi.org/10.1002/ajim.20986
 
[8]Weiner, J., Barlow, L. and Sjogren, B. (2007) Ischemic Heart Disease Mortality among Miners and Other Potentially Silica-Exposed Workers. American Journal of Industrial Medicine, 50, 403-408. http://dx.doi.org/10.1002/ajim.20466
 
[9]Hendryx, M. (2009) Mortality from Heart, Respiratory, and Kidney Disease in Coal Mining Areas of Appalachia. International Archives of Occupational and Environmental Health, 82, 243-249. http://dx.doi.org/10.1007/s00420-008-0328-y
 
[10]Hendryx, M. and Zullig, K.J. (2009) Higher Coronary Heart Disease and Heart Attack Morbidity in Appalachian Coal Mining Regions. Preventive Medicine, 49, 355-359. http://dx.doi.org/10.1016/j.ypmed.2009.09.011
 
[11]Brook, R.D., Franklin, B., Cascio, W., Hong, Y., Howard, G., Lipsett, M., Luepker, R., Mittleman, M., Samet, J., Smith Jr., S.C. and Tager, I. (2004) Air Pollution and Cardiovascular Disease: A Statement for Healthcare Professionals from the Expert Panel on Population and Prevention Science of the American Heart Association. Circulation, 109, 2655-2671. http://dx.doi.org/10.1161/01.CIR.0000128587.30041.C8
 
[12]Sjogren, B. (1997) Occupational Exposure to Dust: Inflammation and Ischaemic Heart Disease. Occupational and Environmental Medicine, 54, 466-469. http://dx.doi.org/10.1136/oem.54.7.466
 
[13]Fernandez Rego, G., Ocio Achaerandio, G., Gonzalez Cuervo, V., Rodriquez Menendez, C., Martinez Gonezalez, C. and Alvarez Alvarez, C. (1991) Presence of Acute Phase Response in Coal Workers’ Pneumoconiosis. British Journal of Industrial Medicine, 48, 193-195.
 
[14]Agency for Healthcare Research and Quality (2007) Comparative Effectiveness of Percutaneous Coronary Interventions and Coronary Artery Bypass Grafting for Coronary Artery Disease. DHHS (AHRQ) Publication No. 08-EHC002- EF. http://www.effectivehealthcare.ahrq.gov/ehc/products/15/55/CER_PCI_CABGMainReport.pdf
 
[15]Agency for Healthcare Research and Quality (2011) Comorbidity Software. http://www.hcup-us.ahrq.gov/toolssoftware/comorbidity/comorbidity.jsp
 
[16]US Census Bureau (2010) The United States Census Bureau. http://www.census.gov/
 
[17]Agency for Healthcare Research and Quality (2011) State Inpatient Databases (SID). http://www.hcup-us.ahrq.gov/sidoverview.jsp
 
[18]van Walraven, C., Austin, P.C., Jennings, A., Quan, H. and Forster, A.J. (2009) A Modification of the Elixhauser Comorbidity Measures into a Point System for Hospital Death Using Administrative Data. Medical Care, 47, 626-633. http://dx.doi.org/10.1097/MLR.0b013e31819432e5                              eww150215lx
标签：

评论

发表评论

此博客中的热门博文

A Comparison of Methods Used to Determine the Oleic/Linoleic Acid Ratio in Cultivated Peanut (Arachis hypogaea L.)

Cultivated peanut ( Arachis hypogaea L.) is an important oil and food crop. It is also a cheap source of protein, a good source of essential vitamins and minerals, and a component of many food products. The fatty acid composition of peanuts has become increasingly important with the realization that oleic acid content significantly affects the development of rancidity. And oil content of peanuts significantly affects flavor and shelf-life. Early generation screening of breeding lines for high oleic acid content greatly increases the efficiency of developing new peanut varieties. The objective of this study was to compare the accuracy of methods used to classify individual peanut seed as high oleic or not high oleic. Three hundred and seventy-four (374) seeds, spanning twenty-three (23) genotypes varying in oil composition (i.e. high oleic (H) or normal/not high oleic (NH) inclusive of all four peanut market-types (runner, Spanish, Valencia and Virginia), were individually tested ...
发表评论
阅读全文

Location Optimization of a Coal Power Plant to Balance Costs against Plant’s Emission Exposure

Fuel and its delivery cost comprise the biggest expense in coal power plant operations. Delivery of electricity from generation to consumers requires investment in power lines and transmission grids. Placing a coal power plant or multiple power plants near dense population centers can lower transmission costs. If a coalmine is nearby, transportation costs can also be reduced. However, emissions from coal plants play a key role in worsening health crises in many countries. And coal upon combustion produces CO 2 , SO 2 , NO x , CO, Metallic and Particle Matter (PM10 & PM2.5). The presence of these chemical compounds in the atmosphere in close vicinity to humans, livestock, and agriculture carries detrimental health consequences. The goal of the research was to develop a methodology to minimize the public’s exposure to harmful emissions from coal power plants while maintaining minimal operational costs related to electric distribution losses and coal logistics. The objective was...
发表评论
阅读全文

Evaluation of the Safety and Efficacy of Continuous Use of a Home-Use High-Frequency Facial Treatment Appliance

At present, many home-use beauty devices are available in the market. In particular, many products developed for facial treatment use light, e.g., a flash lamp or a light-emitting diode (LED). In this study, the safety of 4 weeks’ continuous use of NEWA TM , a high-frequency facial treatment appliance, every alternate day at home was verified, and its efficacy was evaluated in Japanese individuals with healthy skin aged 30 years or older who complained of sagging of the facial skin.  Transepidermal water loss (TEWL), melanin levels, erythema levels, sebum secretion levels, skin color changes and wrinkle improvement in the facial skin were measured before the appliance began to be used (study baseline), at 2 and 4 weeks after it had begun to be used, and at 2 weeks after completion of the 4-week treatment period (6 weeks from the study baseline). In addition, data obtained by subjective evaluation by the subjects themselves on a visual analog scale (VAS) were also analyzed. Fur...
发表评论
阅读全文