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ABSTRACT
Cancers
in young children in early growing age was a short PBS (KQED) report
(11/21/2014), but without informational source, which prompted a Google
search. Sports-associated injuries with medical healing treatments
concluded that there were no association between these body traumas and
cancer development. But there are other activities from young children,
such as “dare-devil” skateboard and bicycling meter-high jumping with
potential high energy falls, to serious broken-bone injuries. Falls of
children are among the most common causes of US emergency response. The
question is why bodily injury is associated with cancer-development? An
answer to this question was exemplified by osteosarcoma in young
children, which suggested that injury to growing points of bone and
surrounding soft tissue cells would elicit a repair process (wound
healing process) producing polyploidy with diplochromosomes. The
non-mitotic reductive division of such 4-chromatid chromosomes has been
shown in vitro to produce pathological cancer-like phenotypes, including gain of a proliferative advantage.
KEYWORDS
Endomitosis, Endotetraploidization, Diplochromosomes, Reductive Division, Genomic Change, Proliferative Advantage, Wound Healing
Cite this paper
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