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Proximal White Onychomycosis in an Immunocompetent Patient: A Case Report

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http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53522#.VMdI-SzQrzE

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ABSTRACT
Objective: Onychomycosis is a diagnosis of fungal organisms in the nail unit. It frequently occurs in both the immunocompetent and immunocompromised patient. A variant of onychomycosis is proxiaml onychomycosis that occurs on the most proximal aspect of the nail. Proximal onychomycosis is known to be commonly associated with immunocompromised status. Study Design: A case report of a veteran who presented a dermatology clinic with complaint of solitary nail discoloration that was recalcitrant to over-the-counter therapy including topical hydrogen peroxide and foot soaks without improvement. Results and Conclusions: This individual case report demonstrates that pedal proximal onychomycosis can be associated with non-dermatophyte organisms, identified as Fusarium species, in immunocompetent individuals. The finding of pedal proximal onychomycosis caused by a Fusarium non-dermatophytic mold has not been reported. The veteran was successfully cured of the condition with treatment via oral terbinafine for a ninety-day course while monitoring patient’s liver function test for any complications.
 
Cite this paper
Schmidt, B. and Holmes, C. (2015) Proximal White Onychomycosis in an Immunocompetent Patient: A Case Report. Case Reports in Clinical Medicine, 4, 41-44. doi: 10.4236/crcm.2015.41010.
 
References
[1]Ahn, K.J. (1994) A Case of White Superficial Onychomycosis. Korean Journal of Dermatology, 32, 931-933.
 
[2]Habif, T.P., Ed. (2010) Clinical Dermatology. 5th Edition, Saunders Elsevier, Philadelphia, 491-523.
 
[3]Hay, R.J. (2009) Dermatophytosis and Other Superficial Mycoses. In: Mandell, G.L., Bennett, J.E. and Dolin, R., Eds., Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 7th Edition, Churchill Livingstone Elsevier, Philadelphia, Chapter 267.
 
[4]Phillips, P. (1996) New Drugs for the Nail Fungus Prevalent in Elderly. JAMA, 276, 12-13.
http://dx.doi.org/10.1001/jama.1996.03540010014007
 
[5]Elewski, B.E. and Hay, R.L. (1996) Update on the Management of Onychomycosis: Highlights of the Third Annual International Summit on Cutaneous Antifungal Therapy. Clinical Infectious Diseases, 23, 305-313.
 
[6]Zaias, N., Glick, B. and Rebell, G. (1996) Diagnosing and Treating Onychomycosis. The Journal of Family Practice, 42, 513-518.
 
[7]Gupta, A.K., Taborda, P., Taborda, V., Gilmour, J., Rachlis, A., Salit, I., et al. (2000) Epidemiology and Prevalence of Onychomycosis in HIV-Positive Individuals. International Journal of Dermatology, 39, 746-753.
http://dx.doi.org/10.1046/j.1365-4362.2000.00012.x
 
[8]Tlacuilo-Parra, A., Guevara-Gutierrez, E., Mayorga, J., Garcia-De La Torre, I. and Salazar-Paramo, M. (2003) Onychomycosis in Systemic Lupus Erythematosus: A Case Control Study. The Journal of Rheumatology, 30, 1491-1494.
 
[9]Schlefman, B.S. (1999) Onychomycosis: A Compendium of Facts and a Clinical Experience. The Journal of Foot & Ankle Surgery, 38, 290-302. http://dx.doi.org/10.1016/S1067-2516(99)80072-6
 
[10]Odom, R.B. (1996) New Therapies for Onychomycosis. Journal of the American Academy of Dermatology, 35, S26-S30. http://dx.doi.org/10.1016/S0190-9622(96)90067-5
 
[11]Elewski, B.E. (1993) Clinical Pearl: Proximal White Subungual Onychomycosis in AIDS. Journal of the American Academy of Dermatology, 29, 631-632. http://dx.doi.org/10.1016/S0190-9622(08)81867-1
 
[12]Weinberg, J.M., Koestenblatt, E.K., Don, P.C., White, S.M., Stein, M.N. and Bamji, M. (1999) Proximal White Subungual Onychomycosis in the Immunocompetent Patient: Report of Two Cases and Review of the Literature. Acta Dermato-Venereologica, 79, 81-95.
 
[13]Piraccini, B.M., Morelli, R., Stinchi, C. and Tosti, A. (1996) Proximal Subungual Onychomycosis Due to Microsporum canis. British Journal of Dermatology, 134, 175-177.
http://dx.doi.org/10.1111/j.1365-2133.1996.tb07863.x
 
[14]Baran, R., Tosti, A. and Piraccini, B.M. (1997) Uncommon Clinical Patterns of Fusarium Nail Infection: Report of Three Cases. British Journal of Dermatology, 136, 424-427.
http://dx.doi.org/10.1111/j.1365-2133.1997.tb14959.x
 
[15]Dordrain-Bigot, M.L., Baran, R., Baixench, M.T. and Bazex, J. (1996) Fusarium Onychomycosis. Annales De Dermatologie et De Venereologie, 123, 191-193.
 
[16]Silver-Lizama, E. and Logemann, H. (1996) Proximal White Subungual Onychomycosis in AIDS. International Journal of Dermatology, 35, 290-291.
http://dx.doi.org/10.1111/j.1365-4362.1996.tb03006.x
 
[17]Noppakun, N.M. and Head, E.E. (1986) Proximal White Subungual Onychomycosis in a Patient with Acquired Immune Deficiency Syndrome. International Journal of Dermatology, 25, 586-587.
http://dx.doi.org/10.1111/j.1365-4362.1986.tb04705.x
 
[18]Tosti, A., Piracinni, B.M. and Lorenzi, S. (2000) Onychomycosis Caused by Nondermatophytic Molds: Clinical Features and Response to Treatment of 59 Cases. Journal of the American Academy of Dermatology, 42, 217-224.
http://dx.doi.org/10.1016/S0190-9622(00)90129-4
 
[19]Hilmioglu-Polat, S., Metin, D.Y., Inci, R., Dereli, T., Kilinc, I. and Tümbay, E. (2005) Non-Dermatophytic Molds as Agents of Onychomycosis in Izmir, Turkey—A Prospective Study. Mycopathologia, 160, 125-128.
http://dx.doi.org/10.1007/s11046-005-6872-z
 
[20]Gupta, A.K., Jain, H.C., Lynde, C.W., Macdonald, P., Cooper, E.A. and Summerbell, R.C. (2000) Prevalence and Epidemiology of Onychomycosis in Patients Visiting Physicians’ Offices: A Multicenter Canadian Survey of 15,000 Patients. Journal of the American Academy of Dermatology, 43, 244-248.
http://dx.doi.org/10.1067/mjd.2000.104794                                                                         eww150127lx

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