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http://www.scirp.org/journal/PaperInformation.aspx?PaperID=53398#.VMCLVCzQrzE
Affiliation(s)
1Department of Psychology, University of Gothenburg, Gothenburg, Sweden.
2Network for Empowerment and Well-Being, University of Gothenburg, Gothenburg, Sweden.
3Institute of Neuroscience and Physiology, Centre for Ethics Law and Mental Health (CELAM), University of Gothenburg, Gothenburg, Sweden.
2Network for Empowerment and Well-Being, University of Gothenburg, Gothenburg, Sweden.
3Institute of Neuroscience and Physiology, Centre for Ethics Law and Mental Health (CELAM), University of Gothenburg, Gothenburg, Sweden.
ABSTRACT
Physical
exercise, whether of aerobic, endurance or resistance types, plays a
central role in establishing and maintaining the integrity of the brain
and central nervous system (CNS). When exercise is adhered to in
conjunction with selective food/drink intake and dietary restriction, it
promotes neurohealth. In this article, we review the interactions of
age and gender, as well as insulin and diabetes, with exercise,
individuals’ cognitive-affective status and its interactions with
exercise propensity, all of which modulate the eventual outcomes of the
influence of exercise upon parameters of neurohealth. The combination of
exercise with dietary restriction provides numerous factors pertaining
to psychological, neurochemical and anti-pathological manifestations of
neurophysiological resilience even through aging. The challenge evoked
by the exercise-diet combination in the body mobilizes a multitude of
adaptive cellular stress-response signaling pathways in neurons
involving neurotrophic factors, anti-inflammatory cytokines, DNA-repair
proteins, macroautophagy, and mitochondrial biogenesis.
Cite this paper
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