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Author(s)
1College of Medical Radiologic Science, Sudan University of Science and Technology, Khartoum, Sudan.
2College of Applied Medical Science, Department of Radiology, Qassim University, Buraidah, Saudi Arabia.
3Radiology and Medical Imaging Department, College of Applied Medical Sciences, Salman bin Abdulaziz University, Al-Kharj, Saudi Arabia.
2College of Applied Medical Science, Department of Radiology, Qassim University, Buraidah, Saudi Arabia.
3Radiology and Medical Imaging Department, College of Applied Medical Sciences, Salman bin Abdulaziz University, Al-Kharj, Saudi Arabia.
A total sample size consisting of 150 Diabetic male
patients has been investigated by ultrasound system General Electric
using gray-scale B-mode imaging with curvilinear transducer 3 MHz to
assess the impact of diabetes in kidney morphology and it is distributed
in Sudan. The collected data were the patient age, height, weight,
kidneys size, ultrasound findings of involved kidneys, and duration of
diabetes and residence region. The analyzed data show that the diabetes
has been as endemic disease in central Sudan (Khartoum & Jazeera)
representing 55% and in the west of Sudan representing 38%. The BMI of
diabetic patients has been significantly (R2 = 0.6) decreasing following aging. The kidney size increases significantly as R2
= 0.75 and 0.6 for left and right kidney respectively. Their
correlation is fitted in the following equations: y = 3.95x + 27.26 and y
= 2.41x + 35.12 for the left and right kidney respectively. The impact
of duration was a reduction in size significantly as R2 =
0.61 and 0.55 with a correlation fitted in the following equations: y =
?2.22x + 139.9 and y = ?1.51x + 96.59 for the left and right kidney
respectively. The mean kidney length was (14.5 cm) and the renal cortex
in the range of 2 - 2.3 cm, the kidneys size were so enlarged as 92.4 ±
11.7 and 121 ± 17.1 for the right and left kidney respectively while in
late case of Diabetes, the kidney is more echogenic, atrophied size with
loss of corticomedullary differentiation.
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Cite this paper
Omer, M. , Eljack, A. , Gar-alnabi, M. , Mahmoud, M.
, Elseid, M. and Edam, G. (2014) Ultrasonographic Characteristics of
Diabetes Impacts in Kidneys’ Morphology. Open Journal of Radiology, 4, 301-308. doi: 10.4236/ojrad.2014.44039.
| [1] | Guyton, A.C. and Hall, J.E. (2006) Text Book of Medical Physiology. 11th Edition, Elsevier Saunders, Philadelphia, 972. |
| [2] |
Dabla, P.K. (2010) Renal
Function in Diabetic Nephropathy. World Journal of Diabetes, 1, 48-56.
http://dx.doi.org/10.4239/wjd.v1.i2.48 |
| [3] |
Danaei, G., Finucane, M.M., Lu,
Y., Singh, G.M., Cowan, M.J. and Paciorek, C.J. (2011) National,
Regional, and Global Trends in Fasting Plasma Glucose and Diabetes
Prevalence since 1980: systematic Analysis of Health Examination Surveys
and Epidemiological Studies with 370 Country-Years and 2.7 Million
Participants. The Lancet, 378, 31-40. http://dx.doi.org/10.1016/S0140-6736(11)60679-X |
| [4] | World Health Organization Global Health Risks (2009) Mortality and Burden of Disease Attributable to Selected Major Risks. WHO Global Health Risks, Geneva. |
| [5] |
Mathers, C.D. and Loncar, D.
(2006) Projections of Global Mortality and Burden of Disease from 2002
to 2030. PLoS Medicine, 3, e442. http://dx.doi.org/10.1371/journal.pmed.0030442 |
| [6] | World Health Organization (2011) Global Status Report on Non-Communicable Diseases 2010. WHO, Geneva. |
| [7] |
Morrish, N.J., Wang, S.L.,
Stevens, L.K., Fuller, J.H. and Keen. H. (2001) Mortality and Causes of
Death in the WHO Multinational Study of Vascular Disease in Diabetes.
Diabetologia, 44, S14-S21.
http://dx.doi.org/10.1007/PL00002934 |
| [8] | World Health Organization (2012) Global Data on Visual Impairments 2010. WHO, Geneva. |
| [9] |
Roglic, G., Unwin, N., Bennett,
P.H., Mathers, C., Tuomilehto, J. and Nag, S. (2005) The Burden of
Mortality Attributable to Diabetes: Realistic Estimates for the Year
2000. Diabetes Care, 28, 2130-2135.
http://dx.doi.org/10.2337/diacare.28.9.2130 |
| [10] |
Bays, H.E., Chapman, R.H. and
Grandy, S. (2007) The Relationship of Body Mass Index to Diabetes
Mellitus, Hypertension and Dyslipidaemia: Comparison of Data from Two
National Surveys. International Journal of Clinical Practice, 61,
737-747. http://dx.doi.org/10.1111/j.1742-1241.2007.01336.x |
| [11] |
Jastaniah, S.D., Alsayed, N.M.,
Awad, I.A., Fida, H.R. and Elniel, H.H. (2013) Evauation of Renal
Disorders in Type 2 Diabetic Patients Using Ultrsonography. Open Journal
of Medical Imaging, 3, 165-170.
http://dx.doi.org/10.4236/ojmi.2013.34024 |
| [12] |
Hricak, H., Cruz, C., Romanski,
R., Uniewski, M.H., Levin, N.W. and Madrazo, B.L. (1982) Renal
Parenchymal Disease: Sonographice Histologic Correlation. Radiology,
144, 141-147.
http://dx.doi.org/10.1148/radiology.144.1.7089245 |
| [13] |
Fiorini, F. and Barozzi, L.
(2007) The Role of Ultrasonography in the Study of Medical Nephropathy.
Journal of Ultrasound, 10, 161-167. http://dx.doi.org/10.1016/j.jus.2007.09.001 |
| [14] | Van Den Noortgate, N., Velghe, A., Petrovic, M., Vandewiele, C., Lameire, N., Voet, D. and Afschrift, M. (2003) The Role of Ultrasonography in the Assessment of Renal Function in the Elderly. Journal of Nephrology, 16, 658-662. |
| [15] | Allan, P., Meire, H., Cosgrove, D., Dewbury, K. and Farrant, P. (2001) The Normal Kidney. In: Clinical Ultrasound: A Comprehensive Text, 2nd Edition, Churchill Livingstone, New York, 513-528. |
| [16] |
Bakker, J., Olree, M., Kaatee,
R., de Lange, E.E., Moons, K.G., Beutler, J.J. and Beek, F.J.A. (1999)
Renal Volume Measurements: Accuracy and Repeatability of US Compared
with That of MR Imaging. Radiology, 211, 623-628.
http://dx.doi.org/10.1148/radiology.211.3.r99jn19623 |
| [17] | Standring, S., Borley, N.R., Collins, P., Crossman, A.R. and Gatzoulis, M.A. (2008) The Anatomical Basis of Clinical Practice (Gray’s Anatomy). 4th Edition, Churchill Livingstone, Edinburgh. |
| [18] | Shcherbak, A.L. (1989) Angriographic Criteria in the Determination of Indications for Organ Preserving Surgery in Renal Artery Occlusion. Klinicheskaia Khirurgiia, 2, 5. |
| [19] |
Guzman, R.P., Zierler, R.E.,
Isaacson, J.A., Bergelin, R.O. and Strandness Jr., D.E. (1994) Renal
Atrophy and Arterial Stenosis. A Prospective Study with Duplex
Ultrasound. Hypertension, 23, 346-347.
http://dx.doi.org/10.1161/01.HYP.23.3.346 |
| [20] | Yamaguchi, S., Fujii, H. and Kaneko, S. (1990) Ultrasonographic Study in Patients with Chronic Renal Failure. Part 1. Ultrasonic Measurement of Renal Size and Analysis of Renal Ultrasonotomograms. Nippon Hinyokika Gakkai Zasshi, 81, 1175-1177. |
| [21] |
Cheong, B., Muthupillai, R.,
Rubin, M.F. and Flamm, S.D. (2007) Normal Values for Renal Length and
Volume as Measured by Magnetic Resonance Imaging. Clinical Journal of
the American Society of Nephrology, 2, 38-45.
http://dx.doi.org/10.2215/CJN.00930306 |
| [22] | Ahmed Awad, M. (2006) Diabetes Care in Sudan Emerging Issues and acute Needs. Diabetes Voice, 51, 1-15. |
| [23] |
Stadler, K., Jenei, V., von
Bolcshazy, G., Somogyi, A. and Jakus, J. (2003) Increased Nitric Oxide
Levels as an Early Sign of Premature Aging in Diabetes. Free Radical
Biology & Medicine, 15, 1240-1251.
http://dx.doi.org/10.1016/S0891-5849(03)00499-4 |
| [24] |
Schutzer, W.E. and Mader, S.L.
(2003) Age-Related Changes in Vascular Adrenergic Signaling: Clinical
and Mechanistic Implications. Ageing Research Reviews, 2, 169-190. http://dx.doi.org/10.1016/S1568-1637(02)00063-6 |
| [25] |
Petrofsky, J., Lee, S. and
Cuneo, M. (2005) Effects of Aging and Type 2 Diabetes on Resting and
Post Occlusive Hyperemia of the Forearm; the Impact of Rosiglitazone.
BMC Endocrine Disorders, 5, 4.
http://dx.doi.org/10.1186/1472-6823-5-4 |
| [26] |
Forbes, G.B. and Reina, J.C.
(1970) Adult Lean Body Mass Declines with Age: Some Longitudinal
Observations. Metabolism-Clinical and Experimental, 19, 653-663. http://dx.doi.org/10.1016/0026-0495(70)90062-4 |
| [27] | Raza, M., Hameed, A. and Khan, M. (2011) Ultrasonographic Assessment of Renal Size and Its Correlation with Body Mass Index in Adults without Known Renal Disease. Journal of Ayub Medical College Abbottabad, 23, 64-68. |
| [28] | Odita, J.C. and Ugbodaga, Cl. (1982) Roentgenologic Estimation of Kidney Size in Adult Nigerians. Tropical and Geographical Medicine, 34, 177-179. |
| [29] | Fernandes, M.M., Lemos, C.C., Lopes, G.S., Madeira, E.P., Santos, O.R., Dorigo, D. and Bregman, R. (2002) Normal Renal Dimensions in a Specific Population. International Brazilian Journal of Urology, 28, 510-515. |
| [30] |
Inomata, S. (1993) Renal
Hypertrophy as a Prognostic Index for the Progression of Diabetic Renal
Disease in Non-Insulin-Dependent Diabetes Mellitus. Journal of Diabetes
and Its Complications, 7, 28-33.
http://dx.doi.org/10.1016/1056-8727(93)90020-Y |
| [31] |
Zerbini, G., Bonfanti, R.N.,
Meschi, F., Bognetti, E., Paesano, P.L., Gianolli, L., Querques, M.,
Maestroni, A., Calori, G., Del Maschio, A., Fazio, F., Luzi, L. and
Chiumello, G. (2006) Persistent Renal Hypertrophy and Faster Decline of
Glomerular Filtration Rate Precede the Development of Microalbuminuria
in Type 1 Diabetes. Diabetes, 55, 2620-2625. http://dx.doi.org/10.2337/db06-0592 |
| [32] | Adibi, A., EmamiNaini, A., Salehi, H. and Matinpour, M. (2008) Renal Cortical Thickness in Adults with Normal Renal Function Measured by Ultrasonography. Iranian Journal of Radiology, 5, 163-166. |
| [33] |
Beland, M.D., Walle, N.L.,
Machan, J.T. and Cronan, J.J. (2010) Renal Cortical Thickness Measured
at Ultrasound: Is It Better than Renal Length as an Indicator of Renal
Function in Chronic Kidney Disease? American Journal of Roentgenology,
195, 146-149. http://dx.doi.org/10.2214/AJR.09.4104 |
| [34] | ANAES (2003) Diagnostic de l’insuffisance rénale chronique chez l’adulte: Texte des recommandations Septembre 2002. Diabetes & Metabolism, 29, 315-324. |
| [35] | Muthusami, P., Ananthakrishnan, R. and Santosh, P. (2014) Need for a Nomogram of Renal Sizes in the Indian Population—Findings from a Single Centre Sonographic Study. Indian Journal of Medical Research, 139, 686-693. |
| [36] |
Bakker, J., Olree, M., Kaatee,
R., de Lange, E.E., Moons, K.G., Beutler, J.J. and Beek, F.J. (1999)
Renal Volume Measurement: Accuracy and Repeatability of US Compared with
That of MR Imaging. Radiology, 211, 623-628.
http://dx.doi.org/10.1148/radiology.211.3.r99jn19623 |
| [37] | Rigalleau, V., Garcia, M., Lasseur, C., Laurent, F., Montaudon, M., Raffaitin, C., Barthe, N., Beauvieux, M.C., Vendrely, B., Chauveau, P., Combe, C. and Gin, H. (2010) Large Kidneys Predict Poor Renal Outcome in Subjects with Diabetes and Chronic Kidney Disease. BMC Nephrology, 11, 1471-2369. eww141203lx |
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