A New Early Gastric Cancer after Subtotal Gastric Resection for Early Cancer: Case Report and Review of the Literature
Read full paper at:
http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52608#.VJy8BcCAM4
http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52608#.VJy8BcCAM4
Author(s)
Although the prognosis of early gastric cancer (EGC) is considered to be
satisfactory, some patients experience tumor relapse after curative surgery.
Both pathogenesis and risk factors of recurrence remain unclear. We describe a
case report of a 49-year-old male who underwent subtotal gastric resection D2A
for angular gastric cancer. Histological examination revealed gastric adenocarcinoma
with low grade of differentiation and colloid areas, intramucosal, and absence
of neoplastic proliferation in the surgical margins, in omental stroma and in
the six examined lymph nodes (pT1, pN0). 11 years later, the same patient underwent
D2 total gastrectomy for gastric cancer in the remnant stomach. New
histological examination revealed again gastric adenocarcinoma, intramucosal,
medium degree of differentiation, no documentable neoplastic proliferation
within the limits of surgical resection, in the thirty-three examined lymph
nodes and in the omentum (pT1, pN0).
Cite this paper
Bruno, L. , Barni, L. , Nesi, G. , Pacciani, S. ,
Masini, G. , Melli, F. , Maltinti, G. , Zalla, T. , Dioscoridi, L. ,
Taddei, A. , Freschi, G. and Bechi, P. (2014) A New Early Gastric
Cancer after Subtotal Gastric Resection for Early Cancer: Case Report
and Review of the Literature. Journal of Cancer Therapy, 5, 1450-1453. doi: 10.4236/jct.2014.514146.
| [1] | Japanese Gastric Cancer Association (1998) Japanese Classification of Gastric Carcinoma. 2nd English Edition. Gastric Cancer, 1, 10-24. http://dx.doi.org/10.1007/PL00011681 |
| [2] |
Degiuli, M. and Calvo, F. (2006)
Survival of Early Gastric Cancer in a Specialized European Center.
Which Lymphadenectomy Is Necessary? World Journal of Surgery, 30,
2193-2203. http://dx.doi.org/10.1007/s00268-006-0179-1 |
| [3] | Borie, F., et al. (2004) Prognostic Factors for Early Gastric Cancer in France: Cox Regression Analysis of 332 Cases. World Journal of Surgery, 28, 686-691. http://dx.doi.org/10.1007/s00268-004-7127-8 |
| [4] | Huang, B., et al. (2011) Long-Term Survival Results and Prognostic Factors of Early Gastric Cancer. Experimental and Therapeutic Medicine, 2, 1059-1064. |
| [5] |
Roviello, F., et al. (2006)
Number of Lymph Node Metastases and Its Prognostic Significance in Early
Gastric Cancer: A Multicenter Italian Study. Journal of Surgical
Oncology, 94, 275-280. http://dx.doi.org/10.1002/jso.20566 |
| [6] | Lee, H.J., et al. (2003) Clinicopathological Analysis for Recurrence of Early Gastric Cancer. Japanese Journal of Clinical Oncology, 33, 209-214. http://dx.doi.org/10.1093/jjco/hyg042 |
| [7] | Nozaki, I., et al. (2010) Risk Factors for Metachronous Gastric Cancer in the Remnant Stomach after Early Cancer Surgery. World Journal of Surgery, 34, 1548-1554. http://dx.doi.org/10.1007/s00268-010-0518-0 |
| [8] |
Oliveira, C., et al. (2013)
E-Cadherin Alterations in Hereditary Disorders with Emphasis on
Hereditary Diffuse Gastric Cancer. Progress in Molecular Biology and
Translational Science, 116, 337-359.
http://dx.doi.org/10.1016/B978-0-12-394311-8.00015-7 |
| [9] |
Komatsu, S., et al. (2012)
Progression of Remnant Gastric Cancer Is Associated with Duration of
Follow-Up Following Distal Gastrectomy. World Journal of
Gastroenterology, 18, 2832-2836.
http://dx.doi.org/10.3748/wjg.v18.i22.2832 |
| [10] | Ikeda, Y., et al. (2005) Effective Follow-Up for Recurrence or a Second Primary Cancer in Patients with Early Gastric Cancer. British Journal of Surgery, 92, 235-239. http://dx.doi.org/10.1002/bjs.4758 |
| [11] | Yamamoto, M., Yamanaka, T., Baba, H., Kakeji, Y. and Maehara, Y. (2008) The Postoperative Recurrence and the Occurrence of Second Primary Carcinomas in Patients with Early Gastric Carcinoma. Journal of Surgical Oncology, 97, 231-235. http://dx.doi.org/10.1002/jso.20946 |
| [12] |
Nasu, J., Doi, T., Endo, H.,
Nishina, T., Hirasaki, S. and Hyodo, I. (2005) Characteristics of
Metachronous Multiple Early Gastric Cancers after Endoscopic Mucosal
Resection. Endoscopy, 37, 990-993.
http://dx.doi.org/10.1055/s-2005-870198 |
| [13] | Kang, G.H., Kim, C.J., Kim, W.H., Kang, Y.K., Kim, H.O. and Kim, Y.I. (1997) Genetic Evidence for the Multicentric Origin of Synchronous Multiple Gastric Carcinoma. Laboratory Investigation, 76, 407-417. |
| [14] |
Ohtani, H., Yashiro, M., Onoda,
N., Nishioka, N., Kato, Y., Yamamoto, S., et al. (2000) Synchronous
Multiple Primary Gastrointestinal Cancer Exhibits Frequent
Microsatellite Instability. International Journal of Cancer, 86,
678-683.
http://dx.doi.org/10.1002/(SICI)1097-0215(20000601)86:5<678::AID-IJC12>3.0.CO;2-O |
| [15] | Ahn, H.S., Kim, J.W., Yoo, M.W., Park, D.J., Lee, H.J., Lee, K.U. and Yang, H.K. (2008) Clinicopathological Features and Surgical Outcomes of Patients with Remnant Gastric Cancer after a Distal Gastrectomy. Annals of Surgical Oncology, 15, 1632-1639. http://dx.doi.org/10.1245/s10434-008-9871-8 |
| [16] |
Ohashi, M., Katai, H., Fukagawa,
T., Gotoda, T., Sano, T. and Sasako, M. (2007) Cancer of the Gastric
Stump Following Distal Gastrectomy for Cancer. British Journal of
Surgery, 94, 92-95. http://dx.doi.org/10.1002/bjs.5538 |
| [17] | Sinning, C., Schaefer, N., Standop, J., Hirner, A. and Wolff, M. (2007) Gastric Stump Carcinoma—Epidemiology and Current Concepts in Pathogenesis and Treatment. European Journal of Surgical Oncology, 33, 133-139. http://dx.doi.org/10.1016/j.ejso.2006.09.006 |
| [18] | Hosokawa, O., Kaizaki, Y., Watanabe, K., Hattori, M., Douden, K., Hayashi, H. and Maeda, S. (2002) Endoscopic Surveillance for Gastric Remnant Cancer after Early Cancer Surgery. Endoscopy, 34, 469-473. http://dx.doi.org/10.1055/s-2002-32007 |
| [19] |
Lee, S.B., Kim, J.H., Kim, D.H.,
Jeon, T.Y., Kim, D.H., Kim, G.H. and Park, D.Y. (2010)
Clinicopathological Characteristics and Prognosis of Remnant Gastric
Cancer. Journal of Gastric Cancer, 10, 219-225.
http://dx.doi.org/10.5230/jgc.2010.10.4.219 |
| [20] |
Morgagni, P., Gardini, A.,
Marrelli, D., Vittimberga, G., Marchet, A., de Manzoni, G., et al.
(2014) Gastric Stump Carcinoma after Distal Subtotal Gastrectomy for
Early Gastric Cancer: Experience of 541 Patients with Long-Term
Follow-Up. The American Journal of Surgery, in Press. http://dx.doi.org/10.1016/j.amjsurg.2014.06.021 eww141226lx |
评论
发表评论