Ocular Response Analyzer to Assess Age-Related Biomechanical Characteristics of the Cornea in a Taiwanese Population
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Author(s)
Department of Ophthalmology, Taipei Medical University Hospital, Taipei, Taiwan
Department of Ophthalmology, School of Medicine, College of Medicine, Taipei Medical University,
Taipei, Taiwan
College of Medicine, National Taiwan University, Taipei, Taiwan
Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Department of Ophthalmology, Cathay General Hospital, Taipei, Taiwan.
Department of Ophthalmology, Cathay General Hospital, Taipei, Taiwan.
Nobel Eye Clinic, Taipei, Taiwan.
College of Medicine, National Taiwan University, Taipei, Taiwan Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Department of Ophthalmology, Cathay General Hospital, Taipei, Taiwan.
Department of Ophthalmology, Cathay General Hospital, Taipei, Taiwan.
Nobel Eye Clinic, Taipei, Taiwan.
College of Medicine, National Taiwan University, Taipei, Taiwan Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Purpose:
To investigate biomechanical properties of the cornea as measured using a
Reichert ocular response analyzer (ORA) in a Taiwanese population. Methods: Basic
demographic data were recorded for 1875 Taiwanese subjects. Corneal hysteresis
(CH), corneal resistance factor (CRF), central corneal thickness (CCT), Goldmann-equivalent
intraocular pressure (IOPg), and corneal-compensated intraocular pressure
(IOPcc) were measured with an ORA. Descriptive statistics and multiple
regression analyses were used to assess and compare relevant factors of the CRF
and CH. Results: In total, 1817 eyes were included in this study. The mean patient
age was 21.4 ± 17.01 years. The mean (±SD) CH and CRF values were 10.6 ± 1.81
and 10.6 ± 1.99 mmHg, respectively. The mean CCT was 560.4 ± 38.53 μm. CH was correlated
with IOPcc, CRF, and CCT. In the multiple linear-regression model, CH was
associated with and affected by IOPcc, CRF, and CCT. In another multiple linear-regression
model, CRF was associated with and affected by IOPcc, CH, and CCT. Conclusions:
Measuring biomechanical properties by Reichert ORA, we found that CH and CRF
values of a Taiwanese population were similar to those other Asian populations
and other races. Our findings provided fundamental data of CH and CRF in a
Taiwanese (ethic Chinese) and also Asian population.
Cite this paper
Wang, T. , Lee, S. , Hsu, W. , Chang, D. and Wang,
I. (2014) Ocular Response Analyzer to Assess Age-Related Biomechanical
Characteristics of the Cornea in a Taiwanese Population. International Journal of Clinical Medicine, 5, 650-656. doi: 10.4236/ijcm.2014.512089.
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