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Application of the COPD Assessment Test (CAT) to Patients with Interstitial Lung Disease

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The COPD Assessment Test was recently developed to assess health status in patients with COPD. However, little was known about its application to patients with interstitial lung disease, so we examined the relationship between the COPD Assessment Test score and respiratory impairment including the clinical picture in subjects with interstitial lung disease. Data were collected retrospectively from 52 consecutive subjects with interstitial lung disease on admission to our facility. All subjects completed the COPD Assessment Test, in which a higher score represented a worse health status. They were also assessed by pulmonary function test, SpO2 during 6-min walk test, and arterial blood gases. The COPD Assessment Test score was negatively correlated with the percentage of predicted forced vital capacity, forced expiratory volume in 1 second, total lung capacity, diffusion capacity of the lung for carbon monoxide, and PaO2 (p = 0.0005, 0.005, 0.0002, 0.0005, and 0.002, respectively). Breathlessness was detected as the high scoring item, while phlegm and sleep were the last affected items. The COPD Assessment Test score was higher in subjects with oxygen desaturation in SpO2 (≥4%) during 6-min walk test (p = 0.0001) and in subjects on home oxygen therapy (p = 0.0007). More than 75% of subjects with oxygen desaturation during walking were classified into a medium or severer impact level of the COPD Assessment Test score, and subjects on home oxygen therapy were classified into a high or severer impact level. PaCO2 in room air and SpO2 at rest did not correlate with the COPD Assessment Test score. The reliability of items in the COPD Assessment Test was 0.87 by Cronbach’s α coefficient. Our results suggest that the COPD Assessment Test may be a candidate for evaluating the health status and impact of disease on patients with interstitial lung disease.
Cite this paper
Someya, F. and Nakagawa, T. (2014) Application of the COPD Assessment Test (CAT) to Patients with Interstitial Lung Disease. Health, 6, 2562-2569. doi: 10.4236/health.2014.619295. 
 

[1] Mineo, T.C., Ambrogi, V., Pompeo, E., Elia, S., Mineo, D., et al. (2004) Impact of Lung Volume Reduction Surgery versus Rehabilitation on Quality of Life. European Respiratory Journal, 23, 275-280.
http://dx.doi.org/10.1183/09031936.03.00025203
[2] Ketelaars, C.A., Schlosser, M.A.G., Mostert, R., Abu-Saad, H.H., Halfens, R.J.G., et al. (1996) Determinants of Health-Related Quality of Life in Patients with Chronic Obstructive Pulmonary Disease. Thorax, 51, 39-43.
http://dx.doi.org/10.1136/thx.51.1.39
[3] Foglio, K., Bianchi, L., Bruletti, G., Porta, R., Vitacca, M., et al. (2007) Seven-Year Time Course of Lung Function, Symptoms, Health-Related Quality of Life, and Exercise Tolerance in COPD Patients Undergoing Pulmonary Rehabilitation Programs. Respiratory Medicine, 101, 1961-1970.
http://dx.doi.org/10.1016/j.rmed.2007.04.007
[4] Spencer, S., Calverley, P.M.A., Burge, P.S. and Jones, P.W. (2001) Health Status Deterioration in Patients with Chronic Obstructive Pulmonary Disease. American Journal Respiratory and Critical Care Medicine, 163, 122-128.
http://dx.doi.org/10.1164/ajrccm.163.1.2005009
[5] Wijkstra, P.J., TenVergert, E.M., van der Mark, T.W., Postma, D.S., Altena, R.V., et al. (1994) Relation of Lung Function, Maximal Inspiratory Pressure, Dyspnea, and Quality of Life with Exercise Capacity in Patients with Chronic Obstructive Pulmonary Disease. Thorax, 49, 468-472.
http://dx.doi.org/10.1136/thx.49.5.468
[6] Tsai, C.-L., Hodder, R.V., Page, J.H., Cydulka, R.K., Rowe, B.H., et al. (2008) The Short-Form Chronic Respiratory Disease Questionnaire Was Valid, Reliable, and Responsive Quality-of-Life Instrument in Acute Exacerbations of Chronic Obstructive Pulmonary Disease. Journal of Clinical Epidemiology, 61, 489-497.
http://dx.doi.org/10.1016/j.jclinepi.2007.07.003
[7] Mahler, D.A., Faryniarz, K., Tomlinson, D., Colice, G.L., Robins, A.G., et al. (1992) Impact of Dyspnea and Physiologic Function on General Health Status in Patients with Chronic Obstructive Pulmonary Disease. Chest, 102, 395-401.
http://dx.doi.org/10.1378/chest.102.2.395
[8] Laviolette, L., Bourbeau, J., Bernard, S., Lacasse, Y., Pepin, V., et al. (2008) Assessing the Impact of Pulmonary Rehabilitation of Functional Status in COPD. Thorax, 63, 115-121.
http://dx.doi.org/10.1136/thx.2006.076844
[9] Chang, J.A., Curtis, J.R., Patrick, D.L. and Raghu, G. (1999) Assessment of Health-Related Quality of Life in Patients with Interstitial Lung Disease. Chest, 116, 1175-1182.
http://dx.doi.org/10.1378/chest.116.5.1175
[10] Bajwah, S., Ross, J.R., Peacock, J.L., Higginson, I.J., Wells, A.U., et al. (2013) Interventions to Improve Symptoms and Quality of Life of Patients with Fibrotic Interstitial Lung Disease: A Systematic Review of the Literature. Thorax, 68, 867-879.
http://dx.doi.org/10.1136/thoraxjnl-2012-202040
[11] Jones, P.W., Harding, G., Berry, P., Wiklund, I., Chen, W.H. and Kline Leidy, N. (2009) Development and First Validation of the COPD Assessment Test. European Respiratory Journal, 34, 648-654.
http://dx.doi.org/10.1183/09031936.00102509
[12] Ringbaek, T., Martinez, G. and Lange, P. (2012) A Comparison of the Assessment of Quality of Life with CAT, CCQ, and SGRQ in COPD Patients Participating in Pulmonary Rehabilitation. COPD: Journal of Chronic Obstructive Pulmonary Disease, 9, 12-15.
http://dx.doi.org/10.3109/15412555.2011.630248
[13] Tsuda, T., Suematsu, R., Kamohara, K., Kurobe, M., Arakawa, I., Tomioka, R., et al. (2012) Development of the Japanese Version of the COPD Assessment Test. Respiratory Investigation, 50, 34-39.
http://dx.doi.org/10.1016/j.resinv.2012.05.003
[14] Jones, P.W., Tabberer, M. and Chen, W.H. (2011) Creating Scenarios of the Impact of COPD and Their Relationship to COPD Assessment Test (CAT) Scores. BMC Pulmonary Medicine, 11, 42.
http://www.biomedcentral.com/1471-2466/11/42
http://dx.doi.org/10.1186/1471-2466-11-42
[15] Nagata, K., Tomii, K., Otsuka, K., Tachikawa, R., Otsuka, K., Takeshita, J., et al. (2012) Evaluation of the Chronic Obstructive Pulmonary Disease Assessment Test for Measurement of Health-Related Quality of Life in Patients with Interstitial Lung Disease. Respirology, 17, 506-512.
http://dx.doi.org/10.1111/j.1440-1843.2012.02131.x
[16] Lama, V.N., Flaherty, K.R., Toews, G.B., Colby, T.V., Travis, W.D., Long, Q., et al. (2003) Prognostic Value of Desaturation during a 6-Minute Walk Test in Idiopathic Interstitial Pneumonia. American Journal of Respiratory and Critical Care Medicine, 168, 1084-1090.
http://dx.doi.org/10.1164/rccm.200302-219OC
[17] Poulain, M., Durand, F., Palomba, B., Ceugniet, F., Desplan, J., Varray, A. and Prefaut, C. (2003) 6-Minute Walk Testing in More Sensitive than Maximal Incremental Cycle Testing for Detecting Oxygen Desaturation in Patients with COPD. Chest, 123, 1401-1407.
http://dx.doi.org/10.1378/chest.123.5.1401
[18] Villalba, W.O., Sampaio-Barros, P.D., Pereira, M.C., Cerqueira, E.M.F.P., Leme Jr., C.A., Marques-Neto, J.F. and Paschoal, I.A. (2007) Six-Minute Walk Test for the Evaluation of Pulmonary Disease Severity in Scleroderma Patients. Chest, 131, 217-222.
http://dx.doi.org/10.1378/chest.06-0630
[19] Wallaert, B., Wemeau-Stervinou, L., Salleron, J., Tillie-Leblond, I. and Perez, T. (2012) Do We Need Exercise Tests to Detect Gas Exchange Impairment in Fibrotic Idiopathic Interstitial Pneumonias? Pulmonary Medicine, 2012, Article ID: 657180.
http://dx.doi.org/10.1155/2012/657180
[20] Martinez, T.Y., Pereira, C.A., dos Santos, M.L., Ciconelli, R.M., Guimaraes, S.M. and Martinez, J.A.B. (2000) Evaluation of the Short-Form 36-Item Questionnaire to Measure Health-Related Quality of Life in Patients with Idiopathic Pulmonary Fibrosis. Chest, 117, 1627-1632.
http://dx.doi.org/10.1378/chest.117.6.1627
[21] Berry, C.E., Drummond, M.B., Han, M.K., Li, D., Fuller, C., Limper, A.H., et al. (2012) Relationship between Lung Function Impairment and Health-Related Quality of Life in COPD and Interstitial Lung Disease. Chest, 142, 704-711.
http://dx.doi.org/10.1378/chest.11-1332
[22] Okubadejo, A.A., Paul, E.A., Jones, P.W. and Wedzicha, J.A. (1996) Does Long-Term Oxygen Therapy Affect Quality of Life in Patients with Chronic Obstructive Pulmonary Disease and Severe Hypoxaemia? European Respiratory Journal, 9, 2335-2339.
http://dx.doi.org/10.1183/09031936.96.09112335
[23] Ferreira, A., Barvey, C., Connors, G.L., Hilling, L., Rigler, J., Farrell, S., et al. (2009) Pulmonary Rehabilitation in Interstitial Lung Disease: Benefits and Predictors of Response. Chest, 135, 442-447.
http://dx.doi.org/10.1378/chest.08-1458                   eww141110lx
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